Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71661	Metolazone	GSE92742	PHH	Human	24h	10uM	EID0387

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	ETV1; WWP1; TAF11; ASCL1; TCF7L1; ADRB2; JARID2; LITAF; SND1; SPDEF; SOX2; ECD; RFX5; NFKB2; NFATC3; TERF1; ZNF140; ZNF268; ESR1; SUB1; ELK4; SIM2; HOXB13; CCNT1; TCF25; HMGB2; TLE2; PITX1; ZNF532; BTG1; HDAC6; EYA1; FOS; ACTL6A; SIX1; NFAT5; PSIP1; ZBTB38; YEATS4; ZFX; IRF1; MAFF; SOX17; ZNF426; TBPL1; TCERG1; COPS5; NKX2-2; SIX2; CBFB; HOXA5; PIR; DEK; NR2F2; RRN3; PTTG1; TEAD1; CREB3L2; PBX1; RAD21; ZNF652; ISL1; JUN; CREM; OSR2; PIAS3; ZFP36L1; CNOT3; CRYM; SMARCA1; PEG3; HOXA4; ZNF195; STAT1; ZNF239; EYA2; MSX1; PGR; RAN; NFE2L3; SMARCD3; SOX10; HDAC9; MEIS1; MYCN; CALR; ZNF587; EHF; NKX3-1; SALL2; HHEX; NR0B1; KAT6B; CHD7; HTATIP2; ZNF91; ZNF160; MAF; MEIS2; NR4A2; TRPS1; ZNF721; ERBB4; MXI1; MYB; JUP; GATA6
Down-regulation	110	ZNF768; NLK; HR; CEBPA; KLF13; HNF1B; TOX4; RNF14; TSC22D3; ESRRA; WWC1; ATF7IP; ZNF443; ZNF189; SUPT6H; NPAT; ZNF22; PAX8; ID2; CDK9; RNF6; SMARCA5; LEF1; ZNF711; RBPMS; ZNF629; ZFP36L2; GFI1; BNC1; PATZ1; KLF7; ZNF529; TCF7L2; ZEB2; SIM1; MXD4; KLF11; ZBTB25; ZBTB18; COPS2; URI1; TSC22D1; CRK; FHL2; PARP1; BCL6; ADNP2; TCF12; MED17; BTAF1; NFATC1; MYC; TAF12; ZEB1; RBM14; TLE1; DAXX; RUVBL2; ZNF165; CNBP; ATF4; SATB1; BACH1; SPEN; MYRF; SP3; NFE2L1; SIAH2; SMAD6; SHOX2; RNF4; MEN1; DRAP1; YBX1; KMT2A; ATF3; TLE4; CCNA2; RBBP8; FOSB; KLF6; HMG20B; USF2; FOXF1; ING2; NRBF2; HIC2; SMAD3; GTF3A; FOSL2; ZBED2; ARID5B; GATA2; ZSCAN18; SCAND1; ID3; ZFHX4; TFEC; ETS2; KLF2; CBX6; KLF10; SOX9; TBL1XR1; FOXG1; HOXB6; EGR3; NFKBIA; AHR; ZNF586