Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71571	Febuxostat	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	EBF2; ASH2L; BATF; IFNB1; NFATC1; GATAD2A; ZBTB24; ZNF410; MAX; ORC2; FOXO3; EGR1; KDM5A; ZBTB43; HDAC2; SIRT7; MTA1; SIX1; CASZ1; CBX6; ZNF384; SOX15; ING3; HOXC8; EWSR1; TCF20; CREB3L2; ZEB2; TAF1D; TCERG1; RBPMS; PURA; SIX2; JARID2; MAFG; TFEB; NR2F2; PHF8; DPF2; LZTS1; CREB5; PRRX1; CXXC1; CITED1; BLM; TRIM25; SSX1; KDM5D; BATF3; ZNF211; ZBTB16; DDIT3; KLF1; MXD1; TBP; SCAND1; KLF4; REPIN1; GFI1; KLF2; NFKBIA; DDX17; BRD2; SMARCD1; NFIC; TCF15; TSC22D1; TOX3; MLLT10; CHD4; YBX1; HIRA; CHD7; TRIM22; NRIP1; APEX1; MED1; NFE2L3; AFF1; EDF1; RBPJ; HNRNPD; MAFF; SAFB2; KLF6; RCOR3; TOB1; ID1; BRD3; PIAS1; IRF5; TCEB2; ZNF692; HMGB3; RXRA; RBBP4; POU2F2; IL16; ZBTB7A; ZNF516; HDAC1; HDAC9; MTF2; ELK1; MEIS1; NFE2; MYCBP; DNAJC1; TBL1XR1; HOXC6; ERBB2; BAZ1A; ITGB3BP; MAFB; MYCN; FOXJ3; FOXF1; BMI1; INSM1; TBL1X; PTTG1; MSX1; DNMT3B; ZMYND8; TWIST1; CITED2; ASCL1; MEOX1; CREB3L1; ENO1; PHF20; SREBF1; ATF3; SPEN; CRK; SOX9
Down-regulation	114	ZFP36L1; INSR; TRPS1; SUZ12; ZNF623; NPAS2; AHR; SIM2; TERF2; SOX18; AGO2; PUF60; ERBB4; ILF2; TRIB3; GON4L; SOX17; CNOT3; CTBP1; WWP1; ZNF580; BCL11A; CREB3; PHIP; SOX3; CTCF; TFAP2C; MYCL; HSF1; ZNF165; ZNF232; TEAD4; TFAP2A; RAD21; ELF5; ZSCAN31; CUX2; HHEX; KLF11; SMAD6; ELK4; THAP11; ZNF32; ZNF589; GTF3A; RORA; HOXD1; HMGA1; NR1H4; ZNF112; NR5A2; ZNF7; CBFB; FOXG1; FOSL2; MNDA; EMX2; POU4F1; PAWR; TAF11; PNRC1; ZNF529; HOXD3; RBL2; TP63; MEIS2; SP100; THAP7; IRF6; JUP; DEK; DLX2; SPDEF; ZNF443; SMARCA1; CHD9; TDP2; SOX13; MKL2; SLC2A4RG; ZNF354A; MTDH; TCF7; MYBL1; URI1; SOX10; KAT2B; BRD7; WWTR1; ZBED2; BTG1; CARM1; TRIM29; ZNF331; FOXM1; WT1; CREBL2; NR4A2; CRYM; IRF8; UBE2B; LOXL2; GATA6; TGFB1; ESR1; MYRF; BHLHE41; TGIF1; CCNH; ETS1; HOXA5; TXNIP; ZNF117; TCEA2