Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71478	Timolol	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	NFKB1; KDM5D; SSRP1; TOX3; UBE2I; KDM5A; SETD3; ATF1; EGR1; EYA1; TMF1; ZNF148; RYBP; PLAGL1; TSG101; CASZ1; GATAD2A; YBX1; SMARCE1; ZEB2; MSC; JARID2; ASH2L; ISL1; DPF2; TAF1D; TRIM25; ORC2; HDAC1; HMGA2; ING3; NR2F2; CREB3L2; CDYL; DDX17; BATF3; ENO1; ZNF217; CTR9; TAF10; NRIP1; TBP; SIX2; CALR; BATF; MED1; CITED1; HMGXB4; BRD3; AFF1; MYCBP; NFKB2; ZNF266; PMF1; HNRNPD; SCAND1; POU5F1B; BRD8; HMGB3; IRF4; BRD2; NFAT5; LITAF; ALX1; DNMT3B; DNAJC1; LIN28A; BLM; BMI1; HEY1; HOXC6; RBBP4; PAXBP1; AIP; TCEB2; ELF3; RBPMS; PCGF2; HLTF; MYCN; NR1D2; FOXF1; BTG1; TLE4; HIPK3; KAT6B; RXRA; PBX3; ZBTB16; SREBF1; ZBTB20; FLNA; TBL1X; ASCL1; ZBTB18; SOX9; SALL1; PUF60
Down-regulation	87	SOX18; TRPS1; LEF1; TERF2; RORA; IFI16; MYBL1; ARL2BP; CD3D; ZNF394; POU2AF1; ZFP36L1; MEIS2; ERBB4; SOX17; VDR; ESR1; PBXIP1; EMX2; RNF6; WWP1; GMNN; CNOT6; BHLHE41; ZNF623; FOSB; CBFA2T3; TRIB3; SMAD7; ZNF83; ZKSCAN1; TFAP2A; TFAP2C; NFYB; CREB3; ZBED2; THAP11; HSF1; MNDA; ZFPM2; SUMO1; CREM; ZNF467; ZHX2; ZNF281; SSX1; PAWR; ID3; TAF9; TAL1; BACH2; WT1; SPDEF; JUN; ZNF232; ELF4; NEUROD1; ZNF165; LHX6; SOX13; EYA2; IRF6; RAD21; RUNX3; TOX; TGFB1; HOXD1; HOXB7; PAX5; ZNF354A; HOXD3; SP140L; ATF3; MECOM; NR4A2; CCNH; MBD2; STAT6; CRK; IRF8; KLF10; CEBPB; CDK7; GATA6; HOXA5; TCEA2; DACH1