Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71459	Penitrem-a	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	CEBPA; EGR1; TSC22D3; CEBPG; ATF4; XBP1; INSR; NFKBIB; RNF10; MXI1; CREB3L2; TMF1; TRPS1; ZNF264; HIPK1; VAX2; DDIT3; ZNF124; KLF9; HIF1A; ZBTB3; ERBB4; ZNF623; TOX3; CBX6; AGO2; LYL1; CAMTA2; ASH2L; BANP; ZNF84; ATF5; ETV6; TOB1; SPIB; HDAC6; CTBP2; BTG1; MED13; CLOCK; TCEA1; ZBTB16; NCOR2; USP22; ZNF551; EMX2; ZNF573; TTF2; HDAC9; POU4F1; FOXO1; ZNF12; NR2C1; TULP3; TWIST1; PNRC1; ZMYM2; FOSB; NFE2L1; CDYL; TLE2; HOXD1; TCF7L2; HOXB2; SOX12; BRD4; ADNP2; TAF9; NR1D2; ZNF189; ZNF107; CITED2; MTDH; SMAD1; EGR3; AFF1; NR4A1; ST18; L3MBTL1; KLF13; MNAT1; RBPMS; MITF; EGR2; HOXB7; FOXD1; IRX5; TRIM16; POU2AF1; TCEA2; BHLHE41; CRK; TGFB1; HOXA5; KLF10; CEBPB; MAFB; MSX1; ESR1; BASP1
Down-regulation	86	EZH2; TFDP1; NFIL3; NKX3-1; HMGB1; TTF1; EYA1; MAF; ETV4; RXRG; PARP1; SP110; RUVBL1; SP3; CARHSP1; RERE; RHOA; GTF2A2; ATF1; TBX3; ABL1; UBE3A; PBXIP1; CAMTA1; BCL11A; FOXF2; PSMC3; DLX2; CREG1; CHD4; E2F6; ZFP36L1; NFE2L3; ZFHX4; HMGXB3; VGLL4; HDAC1; SLC2A4RG; DRAP1; FOXF1; ECD; RBBP4; ZNF226; PFDN5; HMGA2; SMAD4; RNF141; ELK3; SUB1; RBL2; NEDD8; ZNF654; HHEX; TCEB2; SIX2; IRF6; DMTF1; BRD7; NRIP1; IRF2; STAT6; MKL2; RCOR3; ISL1; EDF1; SMARCA1; JUND; SP140L; TSC22D2; ERBB2; TADA3; FLI1; LEF1; AR; TFAP2C; EYA2; JUN; SOX9; NPM1; TCF7; MECOM; FOSL1; STAT3; MYBL2; PBX3; NFKB2