Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71431	Metolazone	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	PAX8; NFKB1; CREB5; ZNF248; NR2F2; HIVEP2; ZNF148; YBX1; AATF; TOB1; HEY1; CALR; ZNF93; ING3; NFYC; DDX17; CTBP2; PRPF6; PHF8; CITED2; ZNF217; NFAT5; MEOX1; NFKB2; PPARGC1A; PNRC1; YWHAB; ZNF266; MGA; TBP; RNF111; MAF; TSC22D1; RBPMS; BRD4; AFF1; ASCL1; JARID2; CITED1; CCNE1; OLIG2; STAT4; MYC; APEX1; TRRAP; BRD2; CDYL; SCAND1; EMX2; NFIC; ZHX2; PITX1; ID4; ENO1; TCF7L2; ZBTB38; PBX1; TP53; HDAC9; MED1; FOXF1; KAT6B; ZNF91; SALL1; LITAF; ZIC1; PUF60; CRK; MSX1; TCEA2
Down-regulation	54	SSBP2; SMAD7; TERF2; IRF1; CDK2; KLF10; WNT4; NKX3-1; ARL2BP; HOXA1; MEIS2; PBXIP1; AHR; RNF6; PPP1R13L; FOSB; VDR; LEF1; VGLL1; ERBB4; HMGB1; CNOT6; HIRA; ZNF165; GFI1B; DLX2; TBX3; CBFA2T3; ZNF232; TAL1; INSM1; NKX2-1; KLF7; RNF138; PEG3; ESR1; MECOM; IFI16; NFE2; POU2AF1; SPDEF; ETS1; HOXB7; CREB1; HIC2; ERG; DACH1; AEBP1; ID3; EYA2; IRF6; MYBL1; ATF3; FOSL1