Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71428	Orphenadrine	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	41	SMAD5; NFKB1; FOXO3; TCF12; GATAD2A; NFKBIB; PHF8; PPRC1; E2F6; MMS19; HOXC6; DPF2; LPIN2; NFKB2; TCEB2; RBPMS; RYBP; HMGA2; PCGF2; ZFP36L1; RHOA; MYC; TBP; SCAND1; NFAT5; TFAM; VGLL4; BBX; BIRC2; TSC22D1; TOX3; HTATIP2; TSC22D2; TBL1X; BASP1; MED1; RXRA; ZBTB18; SOX9; CREB3L1; CRK
Down-regulation	77	BCL11A; INSR; TRPS1; SMAD7; ZNF580; TOB1; TRIB3; HOXD1; CEBPD; AES; URI1; TOPORS; ERBB4; SNAI2; PLAGL1; WWP1; TGIF1; CREBZF; POU4F1; TFAP2C; RORA; LOXL2; CCNE1; ZNF107; TP63; ZNF589; ZNF268; HOXD11; RAD21; TLE2; EYA1; ID1; PRDM2; SLC2A4RG; CAMTA1; ZNF415; TDP2; KLF2; ZNF573; IKBKAP; ZNF654; GRHL2; NCOA3; CBX7; SMARCA2; KLF10; FOXF2; CRYM; FOSL2; CUX1; ID3; DDIT3; NFIC; ST18; IFI16; MNDA; JUN; MYBL1; EP300; ZNF217; NFATC4; MKL2; BHLHE41; TRIM22; WT1; KLF11; ZFP36L2; SOX17; ZSCAN18; TBL1XR1; TOX; EYA2; SMAD1; TCEA2; DACH1; ATF3; ESR1