Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71425	Meclizine	GSE92742	NPC	Human	24h	10uM	EID0386

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	EED; ZNF611; ASH2L; ID4; ZNF721; ZNF43; ZNF160; ZNF85; INSM1; ZNF93; CREBZF; ZNF148; HTATIP2; KLF4; LITAF; DDX17; RFXANK; HOXB2; PQBP1; IRF7; KLF9; CRY1; GATAD2A; ZNF573; ATF3; SHOX2; KLF3; STAT2; ZNF44; MAFF; NFKB2; RBL2; MXI1; JUND; LPIN2; MEOX2; CCNE1; CREB3L2; KLF6; SP100; ZNF91; NFE2L2; TXNIP; FOXF1; ASCL1; NEUROD1; ZSCAN18; TAL1; NR4A1; PEG3; UBE2B; EHF; KLF2; ZNF652; IRF9; TOX3; TCF7L2; E2F3; MAF; ZKSCAN1; ETS2; YWHAB; NFE2; TSC22D2; EDF1; ZEB1; TLE4; EGR3; ZFPM2; GATA6; ZFP36L2; KLF5; ZNF665; MITF; POU2AF1; TCF7; ZIC1; STAT3; MAFB; TCEA2; PBX3
Down-regulation	90	SRCAP; CNOT3; ZNF532; TRIM28; TRPS1; MAZ; USP22; NKX3-1; SERTAD2; POLR2A; CCNA2; NEDD8; GLI2; BCLAF1; BCL6; HOXD11; ZNF787; CIR1; HOXD10; TLE1; RUVBL2; ZMIZ2; PMS1; NR0B1; ZNF580; MTF2; RERE; MEF2A; PSPC1; CBX5; ST18; SPEN; TCF4; ARID1A; POU4F1; KDM5D; ZNF574; JARID2; PPP1R13L; SIX1; POU3F2; PIAS3; ZMYM2; TOPORS; NCOR2; TGFB1; RNF141; MBD4; CITED1; FHL2; MED6; SP3; ZNF552; PBX1; CUX1; MAGED1; TOB1; RUNX1; CALR; SREBF1; PATZ1; CRYM; TSC22D1; ZFHX3; BMI1; LOXL2; EMX2; CHD8; TBL1XR1; CHD3; CUX2; CBX3; MNAT1; BHLHE41; ID3; FLNA; CREB1; MYCL; ZNF281; KDM2A; HMGN3; HDAC9; SALL1; TBL1X; YBX3; MECOM; AEBP1; DACH1; BASP1; NUP62