Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71377	Brinzolamide	GSE92742	NPC	Human	24h	10uM	EID0385

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	EYA2; TCFL5; TERF2; MAZ; PCGF2; MYT1L; HIC2; SAP30; FLNA; REPIN1; TRIM24; ZNF189; PHOX2B; NCOA4; ZNF107; ING1; TBX3; KAT7; ZNF443; ATF5; TCEB2; TP63; PROX1; YBX1; ZBTB18; DEAF1; MSX1; BBX; HSBP1; MED1; ING2; TCF4; TRIM28; TAF5L; TFEB; AES; BAZ1A; TXNIP; SFPQ; CD3D; ESRRG; RFX5; GRHL2; HMGB1; HMGB2; HLF; PIR; PTTG1; MITF; SMARCA2; NFE2L1; ZFHX3; ELF3; URI1; NKX3-1; CREB3L1; HAND1; NR1H3; MBD2; NR1D2; CHD4; TBL1X; ZNF813; ZEB2; ZNF124; POU2AF1; SALL1; NFATC1; ZNF652; ZNF267; KLF10; KDM5D; YWHAB; ZNF394; ZBED1; MAFB; LEF1; SP3; CIZ1; TRIM16; MAF; TFAP2C; DLX5; TCF7; OLIG2; SOX9; EDF1; LZTS1; GATA2; TOB1; PITX1; SMAD1; ELF1; ZNF512B; MAGED1; TGFB1I1; HMGA1; JUNB; MNDA; DNMT3B; ZMYM2; BCL11A; WWTR1; TRIM22; SCAND1; ARID4B; BASP1; CRK
Down-regulation	80	SPEN; PEX2; TRIB3; KAT6B; AEBP1; CERS6; CEBPB; IL16; TULP3; COPS5; POU2F2; SALL2; TCEA1; MYNN; BRF2; CERS4; VPS72; ACTL6A; FOXO1; BPTF; CRYM; RERE; TCF21; MEOX1; ZNF232; MECOM; RBBP8; ANKRD1; PAXBP1; DACH1; RORA; BNC2; YEATS4; NCOA2; IRF9; RBM39; ZMIZ1; HOXB2; LPIN2; BTAF1; PRKDC; AIP; RYBP; BRD8; PEG3; TCF7L2; RUNX1; HBP1; HMBOX1; ZSCAN18; NR0B1; MEIS1; CDK7; ERBB4; TOX; PLAGL1; ZNF410; SERTAD2; BATF3; CALR; ZIC1; SP140L; GATA6; HDAC9; STAT6; TAL1; TRPS1; ASCL1; KAT6A; ZBTB16; SMARCD3; ST18; FOXF2; NFATC3; TCEA2; NFATC4; EGR1; ID2; HOXA5; EGR3