Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71208	Dobutamine	GSE92742	NPC	Human	24h	10uM	EID0385

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	JAK2; ZNF165; IKZF1; HDAC6; RBPJ; NANOG; ZHX3; CD3D; SMARCA2; BCL11B; ZNF107; HDAC1; TRIM29; ZNF562; SKI; NR3C1; SFMBT1; GLI1; KAT5; RSF1; HIPK3; FOXD1; HOXA10; ELK1; MMS19; INSM1; KDM5D; STAT4; RBBP8; REPIN1; MED4; MED7; DDX5; FOXO4; BATF3; MED23; TADA2A; ZBTB38; ZSCAN18; MYB; MDM4; ZBTB25; TLE4; SMARCA5; SATB1; DMRT1; RFX7; ETV1; DEAF1; ZNF587; MDM2; STAT5B; GATA3; FOXO3; ZNF160; ZZZ3; TULP4; SUV39H1; ZNF135; RFX5; RNF141; RBPMS; MSC; TAF12; EGR4; ELK4; ADRB2; ADNP; RBBP5; NFAT5; LHX6; TAF1D; SOX10; POU5F1B; NEDD8; MDFI; SMAD4; RB1; RUNX3; ZNF23; PHF8; MYT1L; TCEB2; HOXA5; SOX4; TFEB; TCF7; TP63; ZBTB18; LPIN2; JARID2; SND1; KAT7; SMAD2; LEF1; ZNF721; CTR9; ZNF189; NFIX; DNMT3B; SIM1; STAT2; CITED1; KAT6B; NKX2-2; SOX12; HLTF; HOXA11; YWHAB; EZH1; NR2F1; LZTS1; SP140L; WNT4; HMG20A; TXNIP; SIAH2; SIM2; NFX1; NPAT; CRY1; MITF; ASH2L; ALX1; PIAS1; RNF10; KLF2; ASCL1; GTF2I; CBFA2T3; STAT5A; ZEB2; BCL11A; PIAS3; EGR3; ZMIZ2; ZEB1; TOX3; SMARCD3; TSC22D3; BCLAF1; NUP62; HNRNPD; PTTG1; MGA; HIVEP2; MYCL; TRIP6; ZNF266; CCNA2; IFI16; NFE2L3; NR2F2; BRD2; FOXF1; MED24; PRKDC; ELK3; DPF2; CIITA; ARID4B; EGR2; TBL1X; BAZ1A; TRIM22; BMI1; CITED2; WT1; PIR; IRX5; TSC22D2; ZNF131; FOSB; ZNF91; ZKSCAN1; KAT6A; BASP1; CRK; TSC22D1; PBX3
Down-regulation	190	HES1; ZMIZ1; TRIB3; VGLL4; SOX17; ZBTB1; ATF1; ZNF232; IRF3; KDM5A; PCGF3; AES; LMCD1; HOXD3; E2F8; CBX4; PAX6; ZNF593; CCNE1; ZNF423; RYBP; PIAS4; TAF6; ERBB4; STAT1; PAWR; NRIP1; SRCAP; CREB1; ZNF768; NR1H4; ZNF444; INSR; MXD3; TULP3; SOX9; MECOM; BRD7; HOXD1; ATN1; RREB1; EMX2; PRDM10; CNOT2; ZFHX3; TCEA1; CARM1; KLF3; CREG1; TAF4; CDC5L; ENY2; MYF6; DLX4; SSBP3; UBE2L3; MED17; NEUROD2; DNMT1; PMS1; ERBB2; HOXC11; SUPT5H; LHX1; AR; ZHX2; MED25; SUPT4H1; GRHL2; BPTF; SSBP2; CREM; HSF1; FOXM1; THAP7; NR0B1; PAXBP1; NEUROD1; SAP130; E2F3; ZNF83; TULP1; ZNF552; TAF5L; CTBP2; ZMYM2; ZNF688; OVOL2; KDM5C; ATF3; PBX1; AGO2; SMARCB1; SUPT3H; ERCC3; OSR2; MAFB; CENPF; DEK; RNF138; FLNA; HIRA; PA2G4; BRF2; VPS72; FUBP1; SMAD7; TFAP2A; KAT2B; HHEX; CEBPG; CEBPD; WHSC1; ERF; PRDM4; CREB3; SALL1; POU2AF1; SOX5; PCGF1; SHOX2; SPI1; NR2F6; FOXJ2; KLF10; ZFP36L1; GATA1; TCF3; SMAD1; ZBED2; CAMTA2; MKL2; NCOA4; ZNF394; JUND; SAP30; ZIC1; DLX5; ELF4; MED21; BHLHE41; TGIF2; NCOA2; HIC2; KLF7; NR5A2; NFE2; FOXF2; IRF8; LITAF; TDP2; ZNF331; IRF7; CTBP1; DLX2; ARID1A; TGFB1; SPIB; RNF6; ID1; FOXA2; SIX2; KLF11; MEIS1; LYL1; ZNF12; ZNF589; MXI1; MED15; WWTR1; MEIS2; HMGN3; RBBP7; CDYL; TCEA2; HDAC9; IRF9; CEBPB; SOX11; JUP; ZNF512B; RUNX1; NFATC4; JUNB; TOB1; NFATC3; PITX2; ID4; ESR1; EGR1