Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71196	Meclizine	GSE92742	NPC	Human	24h	10uM	EID0385

Response Information :

Types	Number	Response transcription factors
Up-regulation	207	ZNF586; SMARCD2; FOSL1; NFKB2; MEF2C; ADRB2; DAXX; ZNF263; MTA1; TRIM32; ABT1; TRIM16; ERF; SUV39H1; LIMD1; NFYA; EPAS1; ZMIZ2; PSPC1; EYA2; TRIM27; DDX54; RNF141; TGIF1; SMARCA1; DMTF1; NR4A3; RBM14; STAT4; AHR; FOXE1; RARB; RXRB; EHMT1; ING1; ESRRA; MXD1; TAF12; ZBTB25; PML; BCL6; DEAF1; BACH1; ZZZ3; ZNF419; RNF14; BBX; ZNF286A; AES; ZNF134; IKZF5; CENPB; BAZ2B; ZSCAN31; ZNF107; PAWR; HMG20B; ZNF165; ELK1; NCOA6; RFX5; ZNF443; NCOA1; RELA; NR0B1; PARP1; TCF25; HOXA1; PIR; ELF3; FOSL2; ZBTB39; SIAH2; FOXC1; POLR2A; ZNF184; CBX4; MEF2A; ZNF672; CHD1; ZNF614; TRIM28; RCOR1; CNOT1; ZBTB1; TBL1X; MYT1L; CREB3L1; CREM; ZNF507; SREBF2; SP3; ZBTB11; CRYM; CREBZF; ITGB3BP; ELF1; TAF10; SNIP1; ZSCAN5A; GTF2I; KLF10; NFYB; HSBP1; REL; SMARCA5; PFDN5; MLLT10; ELK3; IRF6; ZNF394; RB1; CBFB; CDK9; RREB1; RBBP8; ZBTB24; RARG; TBX21; EGR4; UBP1; PRMT2; GATA2; MAML1; STAT2; DRAP1; PHF1; ATF5; ZNF117; SALL1; NFATC1; ZNF304; RNF10; HMGA1; RNF6; USP16; ZNF551; CBFA2T3; ZNF273; MED6; TFCP2; NFKB1; KLF6; NKX3-1; HIPK3; STAT6; ZNF84; ZNF430; HTATIP2; SCMH1; WWC1; TTF1; SP100; CARHSP1; HOXC6; TULP4; HMGA2; TFAP2C; SPDEF; ZNF124; E2F6; MYBL1; EDF1; TSC22D1; NR3C2; PAX5; URI1; ZNF267; ZNF189; ARNTL; TRIP6; ZBTB38; SLC2A4RG; FOXG1; CTNNB1; FLNA; YAP1; BCL11B; RBL2; NCOA4; SATB2; TCF7; MYCL; KLF4; POU4F1; IRF7; ZBTB18; BAZ1A; ZNF512B; YWHAB; MNDA; ZNF329; IRX5; SSBP2; BCL11A; FOXJ3; TRIM22; SOX9; MAGED1; NFATC3; FOSB; NRIP1; ARID4B; BASP1; TOB1; CRK; ESR1
Down-regulation	200	DNMT1; SALL2; PSIP1; SUZ12; RSF1; ZEB1; MEOX1; INSM1; ETS1; HEY1; SPEN; TLE1; PRKDC; KAT2A; XRCC6; ZNF22; COPS5; HIPK2; SNAI2; HOXB5; CDK8; TULP3; HOXB2; PNRC1; RBFOX2; HSF1; VPS72; TCF7L1; TCERG1; DACH1; AEBP1; RAD21; ASCL1; CNBP; SIX2; TFDP1; MEIS1; DEK; TCEA1; ZNF232; SMAD7; TWIST1; RNF138; EWSR1; AATF; BRD8; ZSCAN9; ZNF500; MECP2; CAPN15; TCF7L2; RXRA; HOXA6; HIF1A; HOXB1; YBX3; PEX14; MED14; MYNN; GON4L; TFDP2; PEG3; CHD8; ZNF180; MECOM; PBX1; EED; CHD7; TCF21; PEX2; KAT6B; UBE2L3; ISL1; EYA1; NCOA2; ACTL6A; TERF1; ZNF721; RYBP; INSR; SOX11; ING4; HBP1; CERS6; CERS4; PBX3; UBE3A; NR1I2; HOXB6; ZNF770; WIZ; ZFP69B; NFE2; PSMC3; TFAM; ETV1; FOXO1; SIM1; SMARCB1; TRPS1; TTF2; L3MBTL1; ZIC1; LDB1; ZNF688; ZNF623; NR1H2; ZNF224; ATF2; ZNF611; NR0B2; TGIF2; ZMIZ1; SKI; BNC2; CBFA2T2; SIRT2; RFXANK; CDIP1; GATAD2A; NCOA3; PUF60; SOX17; BRD4; ZFPM2; ZNF268; SPI1; KLF7; LITAF; ZMYND8; ZNF223; HOXD1; SRCAP; PGR; RCOR3; JUND; SUPT6H; CHD4; GFI1B; NUP62; CBX6; MEOX2; RUVBL2; CEBPD; PRRX1; ZNF160; MYC; EN1; IRF8; HEY2; APEX1; PQBP1; HIRA; NFE2L2; NR2F1; CCNA2; KLF13; SMARCE1; THAP11; PHF8; CALR; FOXN3; CDX1; KLF11; CCNC; MED1; TCF4; EMX2; ZBED1; SOX13; CDYL; ST18; ZNF573; CREBL2; TAL1; CITED1; ID2; ZBED2; FOXF2; FOXF1; SREBF1; ID3; ID4; NFATC4; MYB; IKBKAP; CDK7; ELF4; OLIG2; PLAG1; TOX; ZNF131; TP53; SIX1; KAT6A; HOXA5; EGR2; MYCBP; TCEA2; EGR1