Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71148	Brinzolamide	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	67	FOS; BHLHE40; SFPQ; NR3C2; PPARD; CREB3L1; NFKB1; EP300; TP63; NR4A2; CLOCK; BACH2; ELF3; CBX7; TLE2; CTBP2; INSR; MDM2; XBP1; MAGED1; ZSCAN18; JUNB; XRCC6; PQBP1; PPARGC1A; PRDM2; CTNNB1; DEK; ITGB3BP; FOXC1; SIX1; ETS2; MLXIP; CUX1; ZNF131; HIVEP2; ERBB4; NR4A1; RBBP8; LMCD1; HIC2; AEBP1; SMAD1; TRIM16; YWHAB; MTF2; MNAT1; ENO1; ELK3; EMX2; HDAC1; PRRX1; ZBTB1; ZNF281; NPAS2; ELF5; TOX3; MAFG; HOXC10; HOXD1; USP22; NR2F2; BHLHE41; TCEA2; CRK; TRIM22; HOXC6
Down-regulation	62	EN1; KMT2B; BRD2; HDGF; HMGA2; WHSC1; NKX2-2; ZIC1; CD3D; TAF10; POU2AF1; FOXL2; SALL1; JUND; IRF3; CERS6; DACH1; ZNF544; HOXB6; INSM1; BCL11B; SCAND1; SALL2; FOXD1; BAZ2A; PPP1R13L; MYCBP; BTG1; MLXIPL; RXRA; HTATIP2; TRIP6; CHD9; MED1; CALR; HMG20B; KLF5; ZNF264; NR2F6; MEIS1; ZBED2; ATF3; PAX6; FOXO1; FOXF1; NCOA3; ESR1; CEBPB; PBX3; MAF; ZFP36L2; KLF6; ZBTB38; KLF9; MNDA; ID3; NFATC3; MSX1; HOXB7; LEF1; MYBL2; EGR1