Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71111	Pit	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	SUV39H1; GATA3; CEBPD; BHLHE40; SERTAD2; ZNF257; GATA6; TRPS1; TGFB1; ZNF816; TRIP11; TFAP2A; MED12; REL; CEBPG; IFI16; ZNF215; TAF4; GLI3; TP63; TAF4B; TFEC; SATB1; PCGF1; IRF6; SOX13; PPARD; ZNF394; ZNF711; ZNF141; SPI1; ZNF268; HIRA; UBTF; IRF8; ZNF180; GTF2F1; SP2; PRDM14; C1D; ZNF580; ABT1; SOX17; BCL11B; CBX2; ZNF512B; POLR3C; RING1; KDM5C; BNC1; DNAJC2; ZNF107; MYBL1; NR4A2; ZNF589; CCNH; ZNF227; PIAS4; SOX18; CCNC; TAF5L; SSBP3; GLI2; HLX; NR5A2; WT1; TCF7; BHLHE41; CNOT6; SP140L; NKX2-2; JARID2; THAP10; ATN1; GCFC2; NR1H4; ZNF467; NR0B1; MEOX2; VDR; HOXA11; ZNF557; TP53; TEAD4; LHX6; GTF3A; SLC2A4RG; TCF7L1; SSBP2; SOHLH2; MNDA; FOSB; ZNF423; CUX2; MAFB; PFDN5; FOXI1; NEUROD1; MED21; ELF4; PAX6; RNF6; BNC2; CDIP1; HDAC4; JUNB; ZNF43; HIC2; VPS72; SP3; XBP1; ETV5; AHR; YEATS4; SOX9; WWP1; STAT6; ERG; ZNF91; ESR1; PSMC3; PHOX2B; TRIB3; TWIST1; HOXD1; TCF4; TCEA2; MYCL; FOSL2; FOXG1; MAF; RAD21; TRIM22; ZFP36L2; ZNF165; ZBED2; MEIS2; HMGB2; JUP; NFE2; AEBP1; SNAI2; NR2F2; RORA; TFAP2C; ZKSCAN1; EGR2
Down-regulation	153	SMARCA4; USF2; BRD8; CHD4; ETV1; PCBD1; DNMT3B; BAZ1B; ZBTB20; ID1; POU5F1B; RBBP4; E2F2; TSC22D4; HSBP1; SMAD2; CCNA2; GABPB1; SMARCA5; ZNF587; SOX12; ZNF337; IRF4; ASH2L; ZNF24; KDM5B; BRCA1; ZMIZ2; SSRP1; HNRNPD; SCAND1; KLF5; CBX3; RUVBL2; RBM39; PITX2; HSF2; HDAC6; KLF2; GTF2IRD1; ATF3; ADNP2; BRD3; MITF; PSMC3IP; CDK7; TFAM; ATF4; ZIC1; RCOR3; CREB3L1; NUP62; MAFF; CIR1; NLK; NFAT5; PHF8; LPIN2; FOXJ3; NKRF; ATF1; WHSC1; HOXA7; PURA; PBRM1; POU2AF1; HMGA2; TBP; BRPF1; HMG20B; BTAF1; MED1; UBE2I; CBFB; UBE2B; HMGB3; PHF20; TBL1X; ZNF131; PBXIP1; SMARCE1; TOB1; TCF20; ZSCAN18; RB1; SUPT4H1; CREBZF; MYC; SMARCA1; DDX17; BATF3; TOX3; NCOA2; RBL2; TAF1D; PPARGC1A; ASCL1; ZNF148; SIX2; BASP1; PTTG1; TBL1XR1; HMG20A; BRD2; E2F3; RBPMS; SAP18; TCF12; PEG3; TERF2; XRCC6; MED17; VEZF1; NR4A1; PIAS3; NAB1; ZNF432; TAL1; EED; SHOX2; SMARCD3; SREBF1; TEAD1; FOXF1; WWC1; KDM5A; TRIM16; ZNF672; CRY1; KDM5D; SALL1; ZEB1; ZNF721; ZNF274; ZBTB1; ZBTB18; PBX3; TXNIP; FOXN3; TSC22D2; PCGF2; TCEB2; STAT3; HLTF; NPAS2; TSC22D1; LOXL2; HLF; PAX5; EGR1; ID3; MSX1; SMAD3