Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71098	Nsc-632839	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	339	ADRB2; CEBPD; RARG; NR1H2; HDAC9; GATA2; CBX7; CCNH; BHLHE40; NFKB2; ZNF394; SOX17; JUNB; TRIP11; CAMTA2; CD3D; VGLL1; SOX13; IRF6; NCOA1; KLF13; MED15; PCGF1; DNAJC2; TGFB1; CCNT1; PNRC1; ZNF235; MYCL; FOXJ1; VPS72; NR4A2; REL; OVOL2; FOS; PPARG; OSR2; CLOCK; ZNF331; CSDC2; ATF3; NFE2L2; FOXE1; ERBB4; NFKBIA; TRIM29; EHF; ARID5B; POLR3C; CEBPG; HOXA10; PRDM2; NFYA; PHF1; DLX5; FOSB; ZNF223; IRF9; TFAP2A; TAF5L; IKZF1; NKRF; TAF4B; ESR1; SSBP3; KLF9; BAZ2A; ZNF586; VDR; CDK2; ZNF222; CBX4; MEF2C; KLF11; BHLHE41; KDM4C; TTF2; E2F4; THRA; TP63; IFI16; FOXJ2; NR5A2; PRDM14; ZNF623; SNAI2; JUN; AR; SRCAP; ECD; RBL2; ZNF350; SNAI1; TBX3; ZNF415; TAF1; MXI1; TRIM33; DDIT3; ZNF556; KDM5C; HTATIP2; CCNE1; FEZF2; TP73; NFIC; SMARCD2; E2F8; WDR77; SERTAD2; HLX; CNOT3; TAF1C; SKIL; BRD4; ZNF573; ZNF232; DBP; EMX1; SRY; MED12; EPAS1; ID1; THAP7; SOHLH2; MYBL1; BCL11A; ZIC3; WT1; ZKSCAN4; SSBP2; MLXIP; HOXA4; CBFA2T2; ZBTB39; HSF1; ACTL6B; TEAD3; CDX1; TAL1; TULP4; ST18; NR3C1; EN1; MED21; ZNF354A; ZNF500; MYNN; ZNF195; ZSCAN18; MED14; DLX2; ZNF562; ZSCAN9; CBX6; PRDM1; TULP3; ZNF239; HOXB2; GRHL2; ZXDC; POU6F1; ZNF467; PGR; SOX18; TGIF1; TEAD4; TCF7; SPDEF; TRPS1; LHX6; KLF10; ZNF85; JUP; SPIB; CHD2; IRF1; GCFC2; FOXF2; NR4A3; KLF3; WHSC1L1; HDAC5; MED17; ELF3; NR3C2; CRYM; NHLH1; HIPK1; BTG1; ETS1; ELF4; KAT2A; PROP1; CREB1; SP100; IRF7; CALCOCO1; BNC1; PRMT2; TMF1; PBXIP1; FOXA1; AEBP1; SMAD7; ERG; ZNF835; ZBTB25; TFCP2L1; EZH1; ZNF75D; ZNF124; TDRD3; BCL11B; HIPK2; HIVEP2; TBX1; THAP10; KLF7; TOB1; RFXANK; ASH1L; URI1; CCDC59; TTF1; EYA2; TOPORS; YEATS2; SPI1; TBX21; MECP2; ELK4; ZNF264; ZNF44; GMNN; WNT4; ZNF91; RORA; HOXD1; HOXB5; PPP1R13L; TCF7L2; HBP1; YEATS4; ZNF671; RELA; CEBPB; ZBTB16; NR4A1; USP16; GFI1; ZSCAN32; CSDE1; ZBTB44; ARL2BP; AHR; ZNF165; RBBP8; ZNF557; TFAP2C; RYBP; RUNX3; ACTL6A; FLI1; HOXA11; ZNF266; PTRF; GATA6; CREBL2; MYC; SIRT7; SSX1; SMARCC2; CUX1; GATA1; NFATC4; NAB2; PSMC3; RAD21; FOXI1; IKBKAP; RXRA; RRN3; LEF1; POU2AF1; CREM; ZNF281; MNDA; FOSL2; HOXA1; WWP1; NKX3-1; ZFP36L2; PURA; TRIM22; HLF; FOXA2; TDP2; HOXB6; STAT6; CREB3L2; LYL1; HHEX; TERF1; EGR1; ZNF117; HIC2; NCOA3; SMARCA1; ZEB1; MKL2; HOXC10; ID2; TBX2; EGR4; NR1D2; SMAD1; INSM1; KLF2; KAT2B; PAWR; PRRX1; CDIP1; INSR; BRD2; BNC2; LMCD1; ELF5; NKX2-1; ZKSCAN1; ZBED2; KLF6; EGR3; NFE2; PAX6; MEIS2; ID3; KLF4; TRIB3
Down-regulation	319	SOX11; PUF60; EZH2; HDAC2; PARP1; DRAP1; SMARCC1; PATZ1; RBBP4; RFX5; MED24; ABL1; SMARCA5; TCERG1; SUV39H1; PSIP1; NEDD8; RUVBL2; HNRNPD; NONO; PQBP1; VGLL4; USF2; CBX3; HMGA2; NFIL3; SFPQ; CCNA2; TCF12; GTF3A; ATF4; TBP; NPM1; YBX1; SMAD2; HSF2; CCNC; MAGED1; DNMT3B; BAZ2B; KAT5; ZNF24; APEX1; SCAND1; PRPF6; ZNF146; PMF1; HAND1; HMGN3; WHSC1; TRIM28; EDF1; PCGF2; BRD3; ENO1; ASXL1; CARHSP1; ZFHX4; MED23; TLE4; NCOA4; RBPJ; DDX5; RAN; BRD8; ETV1; PBRM1; BMI1; MTA1; SMARCA4; SNW1; HDAC1; GABPB1; SMARCE1; SREBF1; EWSR1; RBM14; CTNNB1; PHF20; PLAGL1; CTBP1; PTTG1; TRAK1; MTF2; NUP62; DDX54; HDAC6; TP53; BRPF1; ELK1; SMAD4; ZNF721; KAT6A; BIRC2; CBFB; SATB1; ARID4A; PSMC3IP; KDM4A; EYA1; DR1; MED4; BACH2; MYCBP; BATF3; LOXL2; RLF; NRBF2; ZNF787; ZNF282; HMGXB4; ZNF292; NCOR2; BTF3; RNF4; ZFP64; POU3F2; BASP1; BCLAF1; APBB1; CREB5; NAB1; ZNF189; MDFI; SMARCB1; ZBED4; CHD7; HMGB3; ZBTB48; TAF10; ETV5; CEBPZ; ZBTB24; UBE2I; HMG20A; COPS2; ZNF629; CDK8; ZEB2; TRIP6; ZNF334; TSC22D4; ETV4; E2F6; HSBP1; PITX2; FOXJ3; ZMYM2; ZNF76; FHL2; RFX7; ERBB2; RNF138; NFE2L1; ILF2; ATF2; ASH2L; SETD2; DPF2; ZKSCAN7; CENPF; NELFB; TBPL1; ZNF160; MXD3; TCEB2; ELF2; BAZ1B; KDM2A; NKX2-2; TCF4; MMS19; MEOX2; GTF2IRD1; RBBP7; CDK7; CITED1; BLM; CTR9; ZNF672; PRKDC; KDM5D; ZNF410; TBL1XR1; ZZZ3; TBL1X; SIX2; RBM39; NCOA6; CENPB; NCOR1; MBD3; WWTR1; SAP18; WIZ; ATF1; DNAJC1; ZNF8; ZSCAN12; HMG20B; ZFY; PITX1; NFIB; SND1; SIX1; DDX17; ALX1; MTA2; SP3; NLK; ZNF711; KMT5A; HEY2; CBX5; HIRA; REPIN1; E2F3; HOXD10; CNOT6; XRCC6; LPIN2; NR2F2; NKX3-2; TEAD1; ZMIZ2; JARID2; PSPC1; HMGB2; USP22; CASZ1; MED16; ZNF84; TRRAP; RCOR1; PREB; TAF1D; PDLIM1; CNOT1; RERE; ZBTB20; RFC1; ZNF587; SUPT4H1; CERS4; ZNF468; TOX; ARID4B; GTF2A2; HMGB1; ZNF358; MAX; MLX; DEK; ZNF212; TRIM24; ZBTB1; SP110; MAF; AIP; ZNF219; ZNF148; ZNF226; ADNP; BAZ1A; SOX2; VEZF1; RHOA; PIAS2; MAZ; HOXC6; HLTF; BANP; HEY1; DEAF1; CHD1; BCL10; NR2F1; ZNF302; HOXB9; BCL6; DACH1; NRIP1; HDAC3; PRRX2; SAP30; ENY2; MED1; SHOX2; FOXF1; TOX3; ZIC1; CAMTA1; CTBP2; KDM5A; ZNF516; CRY1; SALL1; EGR2; TCEA2; ZNF652; CHD9; STAT5B; PPARGC1A; SOX10; HMGA1; ASCL1; MNAT1; HOXB7; CITED2; ZBTB18; MEIS1; CUX2; FLNA; ETS2; CREG1; MYB; PAX5; SMAD3; SOX9