Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71089	Tracazolate	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	ZNF223; SATB1; ETV1; HEY1; CEBPA; ZNF835; ELF3; HES1; CBX4; IRF8; RSF1; SPI1; NR5A2; ZBTB20; ZNF141; TADA2A; KLF5; PTTG1; ZSCAN9; TAF5L; ZNF528; ZNF573; PCGF3; CREBL2; ZNF180; NEUROD1; ZNF227; BCL3; SSRP1; DEK; CDX2; THAP1; CAMTA2; ETV6; MYCL; INSM1; ZNF711; EN2; FOXA1; NFIB; NLK; SMAD5; TCF7; ZFPM2; ZNF552; UBTF; OLIG2; ZBED4; GATA6; HOXB13; ID2; TRIM29; TFAP2C; RBPMS; DLX5; TRPS1; PAWR; TOX3; NR1H3; PBRM1; ZNF226; SNAI2; NKX3-1; BAZ1A; PITX1; CITED1; TCEA1; NHLH2; MEOX2; NPAS2; TDP2; NAB1; TFAP2A; ZNF124; BHLHE41; HOXD1; ISL1; VPS72; E2F5; PRKDC; GMNN; MITF; MTDH; RBFOX2; ZEB1; ZNF264; PRRX1; IFI16; EHF; HIF1A; WT1; STAT1; TGFB1; ZNF302; ZNF331; EYA2; SOX9; CALR; ERG; TBX3; SPDEF; SMAD7; SOX10; FOXF1; EGR2; MSX1; ID3; TOX; ESR1; USP22; TCF4; LOXL2; MEIS2; DACH1; KLF9; FOXG1; EGR3; LEF1; CRK; TRIB3; NR2F6
Down-regulation	119	THAP4; NFYA; PSPC1; ZNF629; CNOT1; DNMT3B; FUBP1; NR0B2; POU5F1B; GTF3A; SCAND1; MDM2; CCNT1; THRAP3; PQBP1; MGA; ZNF593; FOXK2; MED4; SETD2; MLLT10; PHF2; IKZF5; LIN28A; HIRA; BMI1; TSC22D2; PIAS1; COPS2; ZNF467; MEOX1; RNF10; POU2AF1; IRF4; MYCN; ZNF3; ZMIZ1; KMT2A; CRY1; TBP; ZBTB11; TRIP4; FOXJ3; NOC2L; ELF1; POU2F1; HSBP1; CREBZF; HMGA2; NCOA4; SIRT7; MXD1; SUPT5H; BAZ2A; E2F8; BIRC2; ZBTB1; TLE1; SSBP2; BANP; AFF1; RB1; TBL1XR1; TLE4; NANOG; CDK7; CBX6; EDF1; PBX3; SMARCC2; MED17; TCF25; RCOR3; PSMC3; FOXO3; ATF5; DMTF1; MED23; CARHSP1; PBXIP1; ARID1A; TCEA2; TRIP6; TAF1D; CRYM; ZFP36L2; KLF2; ELK3; MYRF; HEY2; KLF6; NFE2; RBBP4; DDIT3; PIR; TCEB2; CITED2; ERBB2; CREB3L2; YWHAB; HHEX; KAT6B; NR2F2; MAZ; FLNA; ZNF512B; TXNIP; MKL2; BBX; BCL11A; KDM5D; TOB1; HLF; LITAF; PAX5; CREG1; HOXC6; ELF5; EGR1