Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70972	Orphenadrine	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	CBFA2T2; SMARCB1; FLI1; HOXC8; TULP4; IL16; NFKBIA; VPS72; FOXA2; CEBPD; ASH2L; SOX13; MED27; NFKBIB; SSBP3; LIN28A; TRIM25; TCEB2; IRF5; GATA6; BCL11B; APEX1; ZNF266; TFCP2; DBP; YAP1; ST18; DDX17; JARID2; AIP; MYCN; HOXB2; XBP1; EYA1; IFI16; CARHSP1; ZNF133; IRF9; GATA4; HLX; JUN; HMGB3; NR0B1; IRF8; NR1I2; RXRA; RCOR1; NANOG; RHOA; VGLL4; LMCD1; TP63; FOXD1; ID4; DDIT3; NFYC; BNC2; INSM1; JUND; SSBP2; RBPJ; JAK2; MYCL; SSX1; CALR; TGIF1; BCL11A; FLNA; PITX1; TOX3; TRIB3; ENO1; KLF11; EMX2; NKX2-1; CUX2; HOXC10; SOX9; ETS2; KDM5D
Down-regulation	115	NR2F1; BRCA1; CDK2; ZNF267; WWC1; SFPQ; RNF10; CCNH; MBD2; FOXC1; TSC22D3; RBBP8; HDAC6; MED7; SMARCA5; TERF2; UBE2B; KLF5; ZNF304; TOPORS; FUBP1; ZZZ3; MITF; ZNF12; DNMT3B; ZMYM2; NAB1; HMGA1; ZBTB7A; NR3C2; SMAD2; BRIP1; BCLAF1; MDM2; UBP1; COPS2; MED6; MYB; ZNF3; BASP1; TRIM32; ZNF189; ZNF131; ZNF587; SMARCD3; TOB1; MEOX1; RNF4; PMS1; ZNF217; PHF20; CREM; EHF; CHD1; HOXD1; ZNF107; NUP62; TBL1X; ZNF226; PBX1; ING2; ZNF160; NR2F6; CHD9; NR1H3; SOX10; NFYB; MTDH; CRK; EGR3; KLF10; ZKSCAN1; CHD7; PAWR; RNF138; NFIB; CTBP2; YWHAB; ZMIZ1; BBX; PEG3; CREB3; MEIS1; ZNF281; TSC22D2; PIR; BRD4; ZNF721; BHLHE41; ZFP36L1; DMTF1; FOSB; STAT3; E2F3; ELF5; HMG20B; ZBTB18; SMAD1; HLF; TCF4; MECOM; ZNF423; EED; AEBP1; TOX; NR2F2; EGR2; LITAF; USP22; TCEA2; TFAP2C; ID3; SMAD3; MEIS2; EGR1