Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70969	Meclizine	GSE92742	NPC	Human	24h	10uM	EID0384

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	NFKB2; NFKBIB; MDM2; SERTAD2; VDR; MGA; MSL3; ZNF443; AATF; DLX5; KAT8; FOXJ1; MAGED1; HNRNPD; TONSL; ZNF614; DNAJC2; ZFX; CCDC59; SNW1; PMS1; CIZ1; ZNF468; BRCA1; GTF2I; CEBPG; MED6; HSBP1; SIX1; ENO1; RBBP8; MED14; YEATS4; ZBED1; MED12; SAP30; RNF10; ZMIZ2; NELFB; ZNF574; SIM1; FOXI1; TRIM22; BANP; KDM4C; POU4F1; ZNF813; XBP1; DAXX; CBFB; DDIT3; CIITA; MYBL1; FOXG1; BCLAF1; EMX2; SOHLH2; PIR; HMGB2; AES; TGFB1; REL; ID2; EDF1; PRRX2; SP140L; TOX3; ELF5; MTF2; ZNF131; HOXD3; NFYB; MED21; WWTR1; IFI16; SALL1; NFATC3; RB1; DEK; YBX1; ZNF410; CRYM; MNAT1; MED1; ZHX2; RUNX1; KAT2B; DLX2; NKX2-1; LEF1; TGIF1; ERBB2; WWP1; HLF; USP22; ZNF165; ZBTB38; ACTL6A; STAT3; SMAD1; KLF11; NR1D2; MYC; FLNA; MSX1; ERBB4; ZBTB16; TCEA2; HOXC6; HMG20B; NR2F6
Down-regulation	124	NFIL3; SOX11; DRAP1; MEOX1; ZNF224; HEY1; NR1H3; SNAI2; ZNF606; LDB1; IRF7; TGIF2; HMGXB4; RSF1; ZNF500; NAB1; EP300; MITF; MED17; HIPK2; ZNF654; ARNTL; NFAT5; PBX1; SALL2; ZNF345; IRF4; MYCN; HOXB5; NR5A2; PLAGL1; KLF5; CSDE1; SP110; TFEC; RBPMS; KDM2A; TRIP4; ADNP; HINFP; ZNF264; SP100; TCF20; CTBP2; CEBPB; PBX3; HMGB3; CCNA2; HLX; C1QBP; KLF4; ZNF544; TLE4; KLF13; MYRF; LITAF; UBE2I; PTTG1; SREBF1; EGR2; MED13; ID1; CERS6; GATA6; KLF7; XRCC6; BRD8; ZNF467; ZNF3; TBX3; DDX17; NR2F1; ZNF611; SUPT4H1; SCAND1; PEX2; CBX6; ZNF124; BNC2; ATN1; VPS72; TAL1; TAF7; TCEB2; MYCBP; MAFF; MXI1; TRPS1; AR; ZMIZ1; TBPL1; SIX2; MYB; MEIS2; HOXB2; RBPJ; IRF6; ETS2; TOB1; MYCL; ZNF652; ZNF721; ZNF22; CRK; LOXL2; ZFP36L2; PITX1; SMAD7; ZEB1; KDM5D; MKL2; CALR; MAFB; TBL1X; BHLHE41; MYBL2; CITED2; MEIS1; PEG3; TXNIP; NFATC4; TFAP2C; WT1; EGR1