Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70747	Metolazone	GSE92742	ASC	Human	24h	10uM	EID0383

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	RELB; NFKBIB; HES1; NR1H2; CASZ1; SPIB; HHEX; ZNF576; PPARD; DLX2; DLX5; PPP1R13L; TGFB1; BACH2; RARG; ZEB1; CDK9; TERF2; PAX6; PAWR; ZSCAN32; CIZ1; HIVEP3; KLF5; ID3; MEN1; LYL1; KLF13; MKL2; MAFG; PAX5; TAL1; MED25; RERE; NFE2; LHX3; SNAI1; SIX6; MED17; NR1I2; FOXE1; HIPK2; ERF; SOX9; ARNT2; KDM5C; ZBED2; NONO; ATN1; TRIB3; ZBTB17; NKX2-1; AES; MDM4; POU2AF1; ZNF232; ELK3; BASP1; TCF4; SALL1; ID1; LOXL2; BCL11A; YAP1; TCF7L2; ARID1A; ZNF423; WDR77; WNT4; ZNF91; REL; IRF6; TCF7L1; ZNF124; FOXA2; ARID5B; ZFP36L2; FOXD1; HOXA11; TFAP2A; JUN; CALR; INSR; YBX3; TRIM29; ZNF195; TLE4; TP63; DNMT1; THAP11; CREG1; SOX11; ZBTB18; RFX5; BTG1; BIRC2; CITED2; ATF5; ID2; BHLHE41; HEY1
Down-regulation	103	CBX3; WT1; ZNF329; MED21; HMG20A; MYCBP; ZNF140; HIF1A; JARID2; ZEB2; USP22; MAGED1; ZBTB38; NUP62; CERS6; RAD21; MED7; CREB3L1; DNAJC2; ASH2L; GATA6; PDLIM1; ZNF587; TAF11; PBRM1; FOSL2; CNOT2; TRIM24; UBP1; SUMO1; NRIP1; ZNF189; ZNF302; UBE2B; SFMBT1; KLF2; NEDD8; TFAM; RAN; FHL5; SFPQ; SMARCD3; ZNF148; EGR3; ENY2; ATF2; SMARCE1; TRIM22; HMGN3; BANP; WWTR1; EBF2; ZNF468; SMARCA2; PTTG1; ING3; TBL1XR1; REST; HLTF; KAT6A; SMARCA4; MED4; YWHAB; ZNF160; ZNF266; BCLAF1; E2F3; SLC2A4RG; TMF1; ZNF529; YEATS4; SNAI2; DNMT3B; PLAGL1; C1D; ZMYM2; KLF6; SSBP2; CBFB; ACTL6A; MED24; AEBP1; MYRF; PIR; EDF1; ZBTB20; CEBPZ; AHR; BMI1; ZFPM2; RBPMS; SMAD3; PEG3; TXNIP; KLF10; HDAC6; TOX3; EGR2; MNAT1; ZIC1; EMX2; LEF1; GATA2