Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70509	Doxorubicin	GSE92742	ASC	Human	24h	10uM	EID0382

Response Information :

Types	Number	Response transcription factors
Up-regulation	201	MYBL2; YEATS4; FUBP1; PRDM14; MEIS1; ADRB2; GATA6; MED25; PSMC3; E2F1; TRPS1; TBX21; FOXE1; DLX2; GBX1; GFI1B; THRB; RBBP8; SLC2A4RG; HOXB5; ERBB4; ZNF586; JUP; MTF2; E2F4; BARX1; TFAP2C; RING1; NANOG; HIF3A; TAF5L; SOX3; LZTR1; AIRE; POU5F1B; WDR77; TAF6; ETS1; IRF9; LHX3; HDAC9; PBXIP1; SUMO1; ZKSCAN4; NCOA3; ZBED2; BNC2; HSF4; OSR2; LIN28A; ZNF180; ID4; NEUROD6; MECP2; NFATC3; ZNF154; SALL2; NAB2; WT1; ZNF331; HIRA; SPIB; LDB1; BCL11A; WNT4; SOX2; TULP3; ARL2BP; GLI1; EMX1; NEUROD2; PRDM1; ZSCAN18; ARID5B; SSBP3; SOHLH2; NR1H2; NR4A2; PHF1; CUX2; NFE2L3; ZIC3; CERS6; ZNF710; HOXA3; ZNF74; THAP7; ST18; NKX2-1; HHEX; VPS72; NOC2L; HDAC3; ACTL6A; NFAT5; CSDC2; VGLL1; IRF6; ARID1A; E2F8; ESR1; BACH2; RBFOX2; MYBL1; CREM; SOX17; ZNF500; KLF13; AR; ZNF444; ACTL6B; HOXA4; CHD4; BNC1; NR0B2; ARNTL2; CDIP1; EHMT2; TWIST1; ZNF611; CREBL2; MEIS2; CITED2; FOXJ1; NKX3-2; AEBP1; TTF2; CNOT3; TFDP1; PBX3; FOXA2; IRF8; CD3D; RAD21; FOXL2; PBX1; ZBTB44; SRCAP; ZNF467; TCEA1; TCF3; PHIP; SIX6; ZNF91; SMARCB1; SPDEF; BRIP1; ZNF232; KDM5C; ATN1; WHSC1; GRHL2; PIAS4; HMGB3; TAL1; ZMYND11; DBP; JUN; NR5A2; ATF3; HLX; ZNF589; FOXF1; CTBP2; TGFB1; HOXB6; CDK2; CREB3L2; HOXC4; GLI2; ZEB1; PAWR; MYCL; SSBP2; IRF7; ZFPM2; ID3; MYCN; ZNF117; MXI1; ZNF665; NR2F1; HIC2; ZNF423; CALR; TCF4; ZNF512B; ZMIZ1; TCF21; IRF4; NFATC4; PAX6; TRIB3; TFAP2A; VDR; FOXF2; ID1; TCF7L2; MYB; PEG3; LEF1
Down-regulation	249	USP22; MLX; CDK7; FOXO3; FHL2; TSC22D3; CRK; XBP1; PUF60; STAT1; NFKBIA; RNF6; NCOA4; NRIP1; ATF4; MED4; MBD2; GTF3A; SCAND1; NONO; PPARG; CEBPA; CHD1; MAFF; CCNA2; TRIM16; NRBF2; PHF20; MED24; AATF; BAZ1A; TBP; FOSL1; TLE1; NACA; SMAD3; MAGED1; RNF4; SNW1; FOXJ3; ZZZ3; ECD; CCDC59; SAP30; ZNF337; COPS2; HCFC2; TBPL1; ZBED4; IRF2; ELK1; TAF10; SF1; MED23; KLF2; SMARCE1; RAN; MYC; BRD8; DDX17; ADNP2; MAX; TRIM27; ZNF146; HMGB2; ZBTB18; HNRNPD; PATZ1; ZNF148; IKBKAP; CITED1; TRAK1; RBM14; ZBTB11; SETD2; BCL10; SIX1; NKX3-1; ZNF83; RNF10; REPIN1; BIRC2; NCOA6; TMF1; RBPJ; TRIM32; SNIP1; BRD3; BTG1; DDX5; UBE2I; CEBPG; ZNF226; BBX; HSF2; KAT5; NPAS2; ASXL1; TSC22D1; MNT; YBX1; CEBPB; MTDH; SMARCA5; NELFB; SIX2; EDF1; ARID4B; ZFHX4; TDRD3; NPM1; TRIM28; RNF14; ZEB2; APEX1; KAT8; ZFP64; DDX54; FOSL2; TCF12; CDK8; BCL6; KAT7; BAZ1B; ZBTB24; PHF8; LPIN2; NR2F2; ZMYM2; NCOR1; PTTG1; HOXA10; ELF1; EGR4; TAF9; NUP62; CREB3L1; SAP18; YAF2; REST; MNAT1; SMAD7; TERF2; CENPB; ZBTB14; TP53; RARA; CREB5; ING1; CBX3; MED1; PIAS2; SMARCA2; BASP1; DNAJC1; NR1H4; ZNF23; PIR; CBFB; PPARGC1A; CRY1; NCOR2; BRPF1; SERTAD2; SMAD2; JUND; ZBTB16; ZNF189; DPF2; SP140L; SP110; ZNF410; USF2; RELA; CENPF; SFPQ; HOXC6; ITGB3BP; DDIT3; MSX1; SUV39H1; DEAF1; RUVBL2; UBP1; SMARCA4; MEF2A; BMI1; TADA3; TSC22D2; BCLAF1; ETV5; RUNX3; ERG; EGR3; TBL1X; FOXA1; ZHX2; PAX5; TRIP6; CTR9; USP16; ELK3; SUB1; SMARCD2; RFX5; EHF; ZBTB38; HEY1; TAF1D; SREBF1; PQBP1; SCMH1; ATF5; FOXO1; YWHAB; RNF141; ELF5; ING2; EZH2; KDM5D; TOX3; BTAF1; NFYC; ARNTL; JUNB; ENO1; ERBB2; BHLHE41; INSR; PCGF2; KLF6; HTATIP2; STAT5A; EGR2; ID2; SATB2; BCL3; POU4F1; NFIB; RBPMS; SOX9; VGLL4; NFIL3; MEOX1; RORA; ZNF302; SATB1; SMAD1; FOXG1