Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70427	Ilomastat	GSE92742	ASC	Human	24h	10uM	EID0381

Response Information :

Types	Number	Response transcription factors
Up-regulation	295	IRF9; NR4A2; ZNF331; ERBB4; ISL1; DAXX; TGFB1; SALL2; KLF13; ZNF671; SOX13; THAP10; PBX2; PEX14; MTF2; NR2F1; SOX2; ZNF623; SOX11; BAZ2A; SAP130; HHEX; FOXE1; CDIP1; BARX1; ACTL6B; ARID3B; PBX3; MEIS2; PIAS1; E2F4; HSF4; CREB3L2; PHIP; TCF21; INSR; NAB2; RAD21; BCL11A; NR0B2; RSF1; MYBL2; LEF1; DACH1; ZXDC; SPDEF; MYCL; ZNF75D; KAT2B; JUP; ZBTB17; SMARCD1; SMARCC2; ZSCAN18; GRHL2; PEG3; BNC1; MAPK8IP1; MECP2; RUVBL1; NR4A3; GATA1; TRIM22; SOHLH2; HNF1A; ZNF219; SUPT5H; SOX17; HDAC3; CDK9; SSBP3; ELF4; HLX; PRDM14; NR1H2; TCF7L1; PHF1; ELK4; CDX1; EVX1; RBBP8; MEN1; FOXF1; TFDP2; IRF6; ONECUT1; EMX1; TBX21; MLXIP; ZNF211; CEBPZ; PPP1R13L; TOX4; ST18; JAK2; E2F1; ZNF217; SOX3; ZBTB44; NOC2L; ZNF124; SHOX2; NCOA3; TLX2; ARID3A; MTA1; ETV1; CHD2; MED12; VGLL1; PHOX2B; BNC2; SUPT4H1; TERF1; CCNE1; TRPS1; AES; ZNF304; ZIC3; ZSCAN31; NKX2-1; HMGB2; ETV5; CAMTA1; CSDC2; ZNF512B; ESRRG; ETS1; CCNH; ZNF93; MAML1; SCAND1; ZNF154; HIC2; LIN28A; KLF7; TAL1; HSF1; HIRA; ARID5B; MED14; TULP3; ZFPM2; TP73; ZNF768; ZNF180; PSMC3; FOXK2; NR3C2; ZNF586; JUND; PCGF3; SUPT6H; CBX5; ZBED2; ZNF710; MED25; BLZF1; E2F6; PIAS4; ING4; ID4; MNDA; ZNF350; GATA6; DLX2; KMT5A; ZNF701; ZNF711; CBX7; SUPT3H; NANOG; HOXD1; ZNF415; ZNF232; TP63; WWP1; IRF3; NR4A1; STAT4; SNAI1; LHX3; CDC5L; ZNF444; MED15; TRIM29; CIITA; NFE2L3; CBFA2T3; ZNF835; ARID1A; ZNF43; NHLH1; TRIB3; WDR77; SOX21; IFI16; AHR; RARG; HOXB1; TAF5; WNT4; IRF4; ZNF589; VPS72; TBX3; CUX2; SUZ12; MEF2D; WT1; CNOT3; TFAP2A; CHD8; CEBPD; ZNF248; INSM1; ZNF667; FOXI1; CDK2; TLE4; FOXA1; ETV4; ILF2; AGO2; PNRC1; PA2G4; EGR2; KLF2; ZNF556; MEIS1; PRDM1; HMGXB4; BRWD1; TGIF1; PRDM12; MED17; POLR3C; TGIF2; FOXA2; PRDM10; NFATC3; CRYM; POU2AF1; RYBP; SMARCA1; PRDM2; NR2F6; CREM; POU6F2; NEUROD1; SOX18; HOXB2; CHD9; ZNF117; KLF3; FLI1; GMNN; CHD1; E4F1; MYBL1; TCEA1; TCEA2; ZNF33B; BHLHE41; SATB1; NLK; LITAF; CNOT6; TOX; SIX3; HDAC9; FOXM1; IRF8; ZNF654; ZNF423; ZNF264; ZNF580; HOXD3; FOXF2; ARID4B; ZHX2; THAP7; TFAP2C; PAX6; CD3D; PBX1; MYCN; ID1; ESR1; ZFP36L1; SIAH2; SOX9; HES1; KDM5D; THAP11
Down-regulation	255	CRK; TLE1; ATF4; BIRC2; MSX1; SREBF1; MNT; PSIP1; MLX; TSC22D1; NRIP1; TP53; TAF12; BRD8; BAZ1A; HSBP1; CREB5; SMARCE1; TSC22D3; NR1H3; HOXA10; MITF; SAP18; ZNF302; DNAJC2; HTATIP2; MYCBP; PSPC1; RXRA; NR2F2; ATF1; PDLIM1; DNAJC1; NCOR2; ZNF267; KMT2B; TBP; CRY1; MAFB; TBPL1; CCNA2; USF2; SATB2; RNF14; VGLL4; TTF1; FOXO3; ZNF23; TAF1D; WIZ; ERG; SNW1; PHF8; NFE2L1; ELK1; MYC; CEBPA; BASP1; ZBTB11; RBBP4; ENO1; ZNF226; ZFX; FOXJ3; ZNF146; MNAT1; COPS5; GTF2A1; NEDD8; SALL1; ASH2L; PUF60; NFIB; NRBF2; ZKSCAN1; LPIN2; RNF141; DDX5; HEY1; MED6; PPARG; ZBTB24; NR1I2; ZNF160; FOXN2; LOXL2; BAZ1B; HOXB7; HCFC2; NUP62; TAF10; PRKDC; C1QBP; EMX2; ZNF44; RHOA; PREB; TRIM16; ZNF384; KLF12; HDAC6; BRF2; PARP1; ZIC1; DDX17; BTG1; YBX1; TCF7; SMARCD3; FOSL1; PATZ1; GTF2F1; CENPF; MAFF; SETD2; FOXO1; CLOCK; FOXD1; KDM2A; RB1; CBFB; DDIT3; EDF1; ZMIZ2; ATF6; CNBP; ZSCAN12; NPM1; ZNF189; MAF; ZNF410; ZNF721; SUV39H1; STAT3; BRD3; BRD2; NCOA4; RNF6; SMARCA2; ZNF337; BATF3; TRAK1; RNF10; PTTG1; HOXC6; DMTF1; GTF3A; ZBTB1; TBX2; EED; EBF2; PEX2; MTDH; PPRC1; ID2; EZH2; MDM4; BCL3; FOXO4; PURA; PRRX2; CSDE1; PIAS2; ELK3; SND1; ZMYM2; BRD4; POU5F1B; ZNF783; ZNF672; REST; NFKBIA; NCOA1; PPARGC1A; JARID2; TDRD3; MKL2; ZBTB38; FLNA; TFEC; ZEB2; HIVEP2; BRCA1; TEAD1; TCF12; CREG1; CERS6; CARHSP1; SMARCD2; ORC2; ABL1; AATF; KDM5B; RBM39; GATAD2A; HOXB9; CREB3L1; TCEB2; KAT7; HIPK3; NKX3-1; RBM14; CUX1; TMF1; PMS1; GCFC2; DNMT3B; YBX3; SPEN; CNOT1; LMCD1; ZNF32; ZMIZ1; BCL6; CTR9; HDAC2; SIX2; BMI1; IRF7; ARNT; ZNF24; HLTF; PLAGL1; MEF2A; TBL1X; MAZ; MAGED1; KLF9; RBBP5; KLF10; MED1; SMAD2; KDM4C; AR; BCLAF1; ZBTB16; FOXG1; SIX1; RBPJ; SNAI2; BHLHE40; FOXC1; HOXB6; TRIP6; CITED1; ING3; FOS; RFX5; ZBTB18; NFIL3; FHL2; JUNB; KDM5A; STAT5B; EYA2