Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70272	Meclizine	GSE92742	ASC	Human	24h	10uM	EID0381

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	JUN; RREB1; SERTAD2; FOXN3; BRIP1; INSR; SPDEF; PHF20; FOXE1; ING2; WWP1; RBL1; HMGB2; PIAS1; NR3C2; BRD7; LEF1; BRCA2; CHAF1B; JUND; JAK2; TERF1; MEIS2; TFAP2C; GRHL2; ELF1; ZNF552; ZFP36L2; HHEX; ZNF492; MYBL1; HEY2; HOXB7; NKX3-1; SIM2; BANP; ZHX2; TCF7L2; ZNF257; OSR2; ZNF281; NR4A2; SOX18; ETS1; TCF7L1; PRDM10; PRDM2; SSBP3; MYCN; CBFA2T3; POU4F1; ETS2; ATN1; ZEB1; BHLHE41; TDP2; PEG3; TBX3; HOXC10; SNAI2; SIAH2; ZBTB16; KLF2; EGR2; SPEN; FOXM1; SOX9; TRIB3; ZNF589; WT1; TFAP2A; ZFPM2; CDK2; HIC2; ARNT2; HOXC6; DLX5; POU2AF1
Down-regulation	84	TP53; NR2E1; ZSCAN16; ZNF587; ZNF410; ZNF783; BRD2; ZNF721; ZNF160; SREBF1; PRPF6; ZNF83; BATF3; TAF1D; ZBTB1; BRPF1; ZBED2; ZBTB20; ZNF544; RXRB; NFKBIA; SIX2; SMAD7; PMS1; CASZ1; HDAC9; PTTG1; ID2; MAFB; NR1H3; ING3; MZF1; ZKSCAN1; PLAGL2; ZNF432; GTF2IRD1; ZNF444; SAP18; BTG1; ORC2; MDM2; PDLIM1; MITF; KLF5; POU3F2; CHD3; TRIP4; ZNF195; RUVBL2; HMGB1; ZNF394; NUP62; BLM; HES1; ZBTB38; BCL3; HIVEP2; HOXA5; NLK; ZIC1; RBL2; EZH2; IRF7; SIX1; NAB1; HTATIP2; CTR9; MEIS1; BCLAF1; MAF; HLTF; PURA; JARID2; TAF10; ID1; BMI1; DMTF1; BASP1; CREG1; TRIM16; NFAT5; RFX5; NR1D2; KDM5D