Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70226	Leflunomide	GSE92742	SKB	Human	24h	10uM	EID0380

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	EGR1; GATA6; MLXIP; NAB2; HDAC4; ZNF331; SOX2; TGIF1; KDM5C; WT1; NOC2L; ID4; ZNF770; RHOA; PSMC3; MEIS2; NFE2L3; PIAS4; HOXA1; RERE; SCAND1; VPS72; SOX13; HBP1; VGLL1; MED13; BARX1; CNOT3; CTCF; MYRF; TCF21; TCEA2; GMEB2; TCF3; NR4A3; UBE2L3; XRCC6; NR4A1; UBE2I; RUVBL1; CRYM; SIRT7; BNC2; PROP1; ILF2; PRDM12; CARHSP1; MAFF; HLX; ZNF671; RXRA; SIX3; CDX1; TBX21; TCF7L2; HIC2; FOXK2; PBX3; PNRC1; PRDM1; ID1; ZNF232; TP53; DBP; CUX2; CDK9; FOXO1; SMARCB1; IRF9; ZNF593; TFAP2A; PITX1; CTBP2; CREB3L2; KLF7; EGR3; ID2; IL16; HOXB5; NPAS2; FOXL2; CBX4; PIAS1; SOX9; KLF10; HDAC9; JUND; HMGB3; CALR; TOX3; FOXA2; MKL2; TOX; SATB2; ZFP36L1; MNDA; ETS1; WWC1; BACH2; ZNF264; JUP; MAFB; OSR2; ABL1; PAWR; PAX5; EGR2; DLX2; KAT6B; SPDEF; IRF6
Down-regulation	143	CRK; NCOR2; NR3C2; ZNF32; PHF20; TRIM16; PATZ1; YWHAB; HDAC6; PSMD9; ZMYM2; ZNF443; TRIP6; CHD1; RBBP8; ZFHX4; CRY1; MGA; ZIC1; NFIB; COPS2; ZNF587; PPARG; KDM5D; TSC22D3; IKZF5; BAZ1A; RNF10; CCDC59; MTDH; XBP1; EMX2; TDRD3; UIMC1; NUP62; ZFY; COPS5; ZNF384; OLIG2; SP100; GTF3A; MED4; DNMT3B; CTBP1; ARID5A; PSPC1; PBRM1; URI1; PIR; IRF7; ZHX3; REPIN1; FHL5; ZNF23; ING2; RORA; CLOCK; SMAD1; NCOA6; SAP18; MED6; ZNF44; MSX1; ERBB2; HDAC7; MEOX1; TADA3; RNF4; SMAD2; DNAJC2; PTRF; TCF7; ZBTB11; PRMT2; ZNF302; ELF1; RSF1; MAF; CHD3; ZBTB38; ZNF281; DPF2; NEDD8; PIAS3; SMARCE1; FUBP1; ZZZ3; ZNF529; IKBKAP; SMARCA5; WHSC1; NR2F2; TBL1X; UBP1; FOXN3; C1D; RBPMS; SP110; SMARCA4; SIX1; ATF4; BASP1; CTR9; BBX; AHR; CDK8; ELK3; HIVEP2; SMARCA2; MEF2C; TRIM28; BRD8; NFKB1; SOX11; ZNF83; ITGB3BP; EYA2; BMI1; SFPQ; MNAT1; NKX2-2; PCGF2; ENO1; MEOX2; ZMIZ2; ZNF329; SNW1; NR1D2; TGFB1I1; KLF2; HES1; BATF3; MAGED1; SPEN; ZFPM2; ZKSCAN1; HOXC6; TAF1D; TBX3; MECOM; ZBTB18; HMGB2; E2F2