Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70089	Saquinavir	GSE92742	SKB	Human	24h	10uM	EID0380

Response Information :

Types	Number	Response transcription factors
Up-regulation	205	NFKB2; CEBPA; FOS; DAXX; NONO; ZNF131; EP300; PAX8; NR3C1; HMGXB3; APBB1; ZNF532; ZNF3; SAP130; SSX3; GRHL2; ETV1; NFE2L3; MYCN; MED12; ANKRD1; NR4A1; PURA; JUN; AR; ZNF654; DEAF1; GTF2I; THRA; ZNF711; SETDB1; ETV4; NPM1; DNMT3B; ZNF75D; TAF9B; WT1; ZMYND8; PCBD1; RFX5; SATB1; PHOX2A; SALL1; ERCC3; ZFHX3; ESR1; CNOT6; POU2F2; ZKSCAN5; ZSCAN16; ZNF268; HOXC10; NAB2; MAFK; KDM4A; ZNF195; IRF8; MED14; ZNF34; HMG20B; MAFG; BHLHE40; HDAC4; TFAP2C; PKNOX1; THRAP3; BRIP1; NFYC; BPTF; ZNF510; CRYM; ZNF282; SP110; EN2; TAF4B; HOXC11; MGA; MEF2D; ZNF107; STAT3; YWHAB; NR2F2; ARNTL; CUX1; RB1; ZNF335; HDAC1; SOX4; RERE; ZNF671; SSBP3; TEAD3; PHIP; CSDC2; MED15; DEK; ZNF33B; CUX2; BCL11A; SMARCA4; USP16; HAND1; MLXIP; SOX9; ESRRG; HOXB13; SOX18; SOHLH2; LZTR1; TRIB3; SMARCD3; THAP11; RCOR1; BHLHE41; RBBP7; MEN1; ARID3A; ENO1; MECP2; TRIM32; PPP1R13L; IRF9; IKZF1; TSG101; ZSCAN9; SOX3; ZNF45; ARID1A; CTNNB1; ZNF552; USP21; MECOM; ZKSCAN7; MAML1; DMTF1; GABPB1; ZMIZ2; LITAF; TFCP2; DBP; ZSCAN31; ZFHX4; REL; HOXC4; RBBP8; CTBP2; DLX5; NPAS2; CTR9; ID4; FOXO3; SOX17; SOX12; ETS2; ZBTB44; HSBP1; MEIS1; SOX10; TBL1XR1; MAGED1; MYBL1; NKX2-1; PLAGL2; BLM; SND1; TXNIP; HIRA; PLAG1; HMGA1; ZIC3; LYL1; GATA6; ID2; NPAT; ZNF589; PHOX2B; GLI2; SLC2A4RG; BCL6; HES1; NFIB; CHD9; HMGN3; IRF6; MNAT1; SOX13; MYT1L; FOXE1; SP100; WWC1; TFEC; JUP; MYB; NKX3-1; SPDEF; EYA1; SUB1; ELF3; AFF1; TRPS1; MEF2C; ARID5B; TSC22D1; BASP1; TBX3
Down-regulation	231	PDLIM1; YBX3; CRK; NR2F6; BIRC2; HEY1; FOXO1; PSIP1; COPS2; RUNX1; NFYB; EED; ZEB1; ZNF302; HOXB7; MNT; ZNF148; LOXL2; ZNF32; CHD4; INSM1; WWP1; BAZ2A; CNBP; MBD2; HOXA7; BBX; ZNF24; ZMYM2; ZNF667; KLF9; GTF2A1; MAF; TCF3; BRD2; WIZ; BRD4; ZBTB7A; ZNF587; ZNF160; ZNF136; CCNH; CEBPG; BMI1; MYCBP; UBE2I; FLNA; ZNF124; ZNF668; GFI1B; PEX2; CDYL; ZNF91; E2F5; CSDE1; ZNF83; PREB; RNF6; GMEB2; TBP; CDIP1; GATAD2A; ATF3; BATF3; ZNF562; TBL1X; LMCD1; SSBP2; ZNF529; NFKBIB; SAP18; CTBP1; ZNF232; KLF7; ZNF177; USF2; HCFC2; POU2AF1; ZNF224; NR1H2; DR1; ZNF264; VEZF1; FOXF2; EMX2; NCOA2; ZNF44; PBX1; DNAJC1; CHD1; COPS5; CREBL2; HOXB6; KLF13; SMARCA2; THAP1; ZBTB11; TAF9; MED1; CDK9; NFE2L1; BRF2; ING2; MXI1; VGLL4; TOB1; NFATC4; CRY1; ZBTB20; NR2E1; TTF1; ZNF419; TFAM; SUPT4H1; RNF138; CHD7; PIR; HOXD1; ZNF576; ZNF512B; ZBTB38; CCNA2; PITX2; ZNF432; POU3F2; SMARCA5; ABL1; PCGF3; JUND; PSMC3; TSC22D2; KLF11; RFC1; CAPN15; SMARCD2; HOXA10; ZBTB1; PNRC1; ELF4; CCNE1; ID3; TCF7; HDAC6; PTRF; TRAK1; KDM5A; ATF6; NUP62; TCF12; PHF2; CCNT1; ZEB2; NLK; ZNF146; HIPK1; TAL1; PHF8; ZFP36L1; NANOG; ZNF551; ZFP36L2; KLF5; NFAT5; ZNF611; ZNF721; E2F3; ZNF274; ZNF665; TOX3; SPEN; STAT6; ZNF23; HMGB3; TCF7L2; TLE1; ZNF329; SOX15; RYBP; CREG1; TWIST1; CBFB; MYRF; PBX3; HIC2; ASH2L; BCL11B; NCOA4; SIX2; ZNF281; KAT6B; ZNF430; NFE2L2; TP53; EDF1; ZNF573; HLX; KLF2; AEBP1; SMARCB1; LEF1; NRBF2; BTG1; SNAI2; IKBKAP; NCOA1; ZMIZ1; FOXJ3; TOX; KAT2B; KLF4; AHR; NFATC1; HTATIP2; SMAD2; GMNN; BAZ1A; MEIS2; ZNF544; ZKSCAN1; HOXC6; PMS1; PEG3; STAT5A; SOX11; TAF1D; YAP1; HMGB2; HOXA5; MYC; ID1; ZNF586