Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70057	Kn-62	GSE92742	SKB	Human	24h	10uM	EID0380

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	NFATC4; ZNF500; ZNF711; ZNF688; PBX3; TCF20; XRCC6; TULP3; E4F1; ZNF654; ING4; THAP7; MXD3; PIAS4; ZNF117; EP300; ZSCAN9; DLX5; ZSCAN16; ZNF75D; PSMC3; MED27; PAXBP1; ATOH1; PAX6; CBFA2T2; CARHSP1; CTCF; ZNF133; VPS72; HOXA1; ZNF85; ZNF74; INSR; HMX1; NAB2; SOX2; CXXC1; AIP; E2F8; TULP4; THRA; MYBL2; PURA; HMGB3; PRDM2; RING1; PHIP; AR; MYCN; ZKSCAN4; MLXIP; PFDN5; KDM5C; PBXIP1; ZFP36L2; RERE; HIC2; CDK2; RBM39; PROP1; UBE2L3; SIRT7; ZNF331; ZNF232; SMARCB1; ATF3; ST18; CTBP2; TDP2; ZNF215; WNT4; BCL11A; IRF6; BACH2; SRCAP; GATA6; GTF2F1; PBX1; POU2AF1; FOXF2; DDX17; WT1; CUX1; MXI1; MEIS2; ZNF573; MKL2; LEF1; LIN28A; BARX1; SOX13; RXRA; ACTL6A; SSBP3; DBP; JUP; HOXA11; PITX1; RBFOX2; MYBL1; PIAS1; KLF11; HOXB13; CBX4; ATF6; SREBF1; ID4; HIRA; DACH1; SALL2; BNC2; DMTF1; KLF7; ZNF43; TCF4; CDK9; NR1H2; ID1; GRHL2; TCF7L2; ZEB1; ZNF91; TFDP2; ARID4B; TFAP2C; ZMIZ1; CBFA2T3; CREM; TRPS1; ZNF467; CBX7; ZHX2; ZNF665; DLX2; TOB1; CALR; PAWR; KLF4; SSBP2; TBL1XR1; AES; FOXE1; MECOM; SPDEF; NFE2; ABL1; MEF2C; KAT6B; PEG3
Down-regulation	146	XBP1; STAT1; NCOR2; BIRC2; RAN; CRK; FOXD1; WWTR1; IRF8; RNF4; TSC22D3; PIR; BCL10; PCBD1; NFE2L1; CCDC59; CTBP1; PITX2; TRIP6; NRIP1; ECD; NUP62; RBPMS; TRIM22; C1D; ZNF587; HDAC6; EGR1; BAZ1A; MDM2; RNF10; DNAJC2; MSC; MED4; MEOX2; COPS2; CREB3L1; USP22; ZNF226; ZBTB38; SAP18; FOXJ3; CRY1; HOXD1; RNF6; FOXN3; SP100; RBBP8; YBX1; GTF2IRD1; KAT7; ETV5; SFPQ; SMARCA2; KDM5D; ING2; TFCP2L1; TCF7; ZNF146; PRRX1; MED24; PLAGL1; TMF1; TADA3; MYCBP; LMCD1; PRMT2; CTR9; PPARG; SMAD2; RUNX3; SIX1; BATF3; MTDH; ERBB2; ETS2; MED6; SERTAD2; TEAD1; HOXC6; UBP1; ADNP; ENO1; C1QBP; MSX1; REST; SNW1; BASP1; SMARCA4; PTRF; HOXC10; RNF138; RBM14; TAF10; ZNF329; SP110; NR2F2; IRF7; RBPJ; SAP30; HMGN3; ZBED1; FOSB; URI1; AHR; NCOA4; EGR3; PTTG1; HMGA2; ZZZ3; SMARCA5; ZMYM2; PIAS3; TAF7; TRIM28; NFIB; ZBTB11; STAT3; MED1; ZEB2; ITGB3BP; TBL1X; ZNF134; EGR2; REPIN1; HLTF; SUB1; MNAT1; MAGED1; ZBED2; NRBF2; NKX3-1; HOXB2; KLF2; ZFPM2; ASCL1; SOX9; PCGF2; HTATIP2; MAFB; STAT5A; HMGB2; ELK3; ZBTB18; SNAI2; E2F2