Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70023	Methyllycaconitine	GSE92742	SKB	Human	24h	10uM	EID0380

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	PBX3; TDP2; CDX1; GATA2; DAXX; GATA6; FOXI1; TLE4; CDK2; NKX2-5; ZNF33B; TBX1; DEK; RAN; MLXIP; TP73; ATOH1; BCL10; WT1; ZSCAN16; CREB3; MYCN; ZNF573; ZNF195; CD3D; CDC5L; POU2AF1; CDX2; SIX3; WNT4; PRDM12; MED17; TOX; CERS6; ZNF141; TFDP2; ZFHX3; TCF7; GLI3; SOX3; CAMTA1; BCL11A; TWIST1; LEF1; ACTL6B; TAL1; NFE2L3; ZNF117; ZNF354A; ILF2; ID4; HOXB1; ZNF93; TSG101; LYL1; ZNF467; ID3; TFEC; SSBP3; ETS1; E2F3; ZNF557; STAT4; PSMC3; THAP10; HHEX; HOXB13; NKX2-1; DACH1; HOXA5; FOXF1; YWHAB; CENPF; ZNF43; RNF138; TFAP2A; PLAGL1; VDR; KLF3; BCL11B; HIRA; MAF; PAX6; NR2F1; MEIS2; ELF4; ZNF331; RAD21; ZNF239; ZNF589; EGR3; MYBL1; GRHL2; ATF3; SOX11; PEG3; ZNF652; MKL2; FOXA2; INSM1; SPDEF; SMARCB1; CTBP2; ZNF91; ID1; AEBP1; NFE2; HMGB2; HES1
Down-regulation	139	YBX3; CEBPD; RUNX1; ZIC1; HDAC5; NFKBIA; BCL3; HOXC10; HSF2; RBPMS; ARID5A; ZNF384; USF2; SCAND1; ATF4; FOXJ2; NAB1; ZNF148; DNMT3B; PITX1; PATZ1; ELK1; NELFB; BHLHE40; POLR2A; OLIG2; COPS2; POU5F1B; ZMIZ2; KAT7; TRAK1; TRIM16; MTA1; ZNF468; RLF; SMARCA2; MSX1; VGLL4; TULP3; CREB3L1; FOXO4; ZNF146; NEDD8; ZNF587; MYC; ELF1; BBX; NFAT5; MYCBP; ORC2; NKX2-2; PHF8; KDM2A; DNAJC1; FLNA; BRD3; SMARCA4; HEY1; SMARCA1; ING1; EDF1; BAZ1A; PSPC1; UBP1; MED1; BAZ1B; CARHSP1; ZFP36L1; ETV5; JARID2; MEF2A; KDM5A; ZNF329; GABPB1; TRIM28; CCDC59; SMAD3; DPF2; PIR; ARID4A; TRIM29; PHF2; SAP18; ATN1; NFKB1; CITED2; TXNIP; RCOR1; FOXC1; HMGN3; HLF; NUP62; MAGED1; WWTR1; BCL6; MNAT1; HIVEP2; TLE1; NKX3-1; ELF5; SIAH2; NRBF2; SLC2A4RG; KDM5D; ELF3; THAP11; SUB1; ZBTB18; BRPF1; ZMIZ1; EYA2; MAFF; REPIN1; JUND; TRIP6; BASP1; SIX1; TGFB1I1; ESR1; TP63; EMX2; OSR2; SALL1; NR1H2; FOXJ3; HDAC9; FOXG1; TBL1X; PPARD; KLF5; HOXC6; RUVBL2; EZH2; BMI1; KAT6B; MEF2C; NFE2L2; ELK3; E2F2