Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID70007	Scopolamine	GSE92742	SKB	Human	24h	10uM	EID0380

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	PPARG; SUPT3H; CREBL2; PBX3; POU2AF1; INSR; NAB2; NR4A3; ARID3B; BHLHE41; ZNF10; FOXI1; HDAC4; CDC5L; NR1H4; RAN; TFEC; HOXC4; SOX5; KLF4; THAP10; NR3C2; FOXM1; IRF8; IRF1; SP1; HHEX; LHX3; HOXB7; RNF138; ZNF235; CD3D; ZNF215; ZNF331; CAMTA1; CREB1; ZNF528; PRDM14; DDX5; SOX3; NR4A1; PEX14; RAD21; TOX; TAF5L; FOXF1; HOXB6; PSMC3; KLF10; ZNF394; GABPB1; TAF5; SIX3; GATA6; CTBP2; ID4; HIC2; TCF7L2; TFAP2A; ZNF140; FLI1; ZNF239; EPAS1; ZHX2; ZSCAN31; PNRC1; ZNF175; FOXF2; CREB3L2; TRIM29; HIRA; PAX6; ERBB4; TFAP2C; KLF11; HOXB5; PEG3; NR1H3; ASCL1; TRPS1; ZFPM2; HMGB2; CBX4; KLF3; ZNF589; ZNF573; NR5A2; SALL1; MNDA; TAL1; MAFB; BCL11B; HOXA5; VDR; MEIS2; ZNF467; RXRA; ZNF200; PAWR; NR2F1; SMAD6; BCL11A; MEF2C; EN1; NR4A2; PBX1; TP63; IRF6; MYBL1; FOXE1; ETS1; TOX3; LEF1; DLX2; ID1; DACH1; KAT6B; ESR1; SNAI2; EGR2
Down-regulation	118	SCAND1; CEBPD; BIRC2; PDLIM1; NCOA6; THAP11; EYA2; PIAS3; PUF60; ZMIZ2; TSC22D3; ZNF358; MED4; FOXD1; USF2; ELK1; SMARCA5; FOXO4; ZNF146; BCL3; ZNF587; TULP4; DPF2; BAZ1A; ZNF148; YBX1; PREB; TERF2; SCMH1; RUNX1; HSF2; IRF7; PCGF3; HMGN3; ZFP64; MYCBP; PLAGL1; TWIST1; UBP1; CRK; BHLHE40; NUP62; NEDD8; RBPMS; TRIM28; TBP; HSBP1; TSC22D4; SSBP2; TOX4; EN2; MSC; STAT3; NFAT5; TRIP4; FLNA; TP53; ELF1; ZNF337; ZNF23; MAGED1; RELA; KLF12; FOXO3; ZMIZ1; TLE1; MSX1; BATF3; POLR2A; ZBTB38; LMCD1; TCEB2; TAF10; PSIP1; BRD3; DRAP1; NFIL3; SMAD3; ELF3; RUNX3; TAF1D; MED1; ZNF410; NAB1; SOX12; KDM5D; KDM2A; MDM2; SNW1; SMARCD2; EHF; CASZ1; TBPL1; ZBTB18; TRIM16; NR2F2; FOSL1; BMI1; NFKB1; RORA; TCF25; TRIP6; ZNF226; SP3; SIAH2; ELK3; NCOA4; SPEN; SIX1; EDF1; RUVBL2; EZH2; PMS1; NFE2L2; RFX5; ERBB2; TRIM22; E2F2