Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69971	Leflunomide	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	215	KDM5A; CERS4; MYBL1; ERBB4; CREB1; ILF2; CTNNB1; ZNF665; ZNF350; ZNF331; CNOT3; SALL2; RXRA; GMNN; ZNF91; PRDM14; NFATC4; SRCAP; ZNF43; ZNF345; ZNF544; E2F4; ATOH1; GRHL2; SOX2; MYBL2; MEIS2; PSMC3; SALL1; TCF7L2; THAP10; RSF1; CCNE1; CEBPG; ZNF224; SPDEF; CBX4; KLF11; RUVBL1; ZFP36L1; E2F1; LITAF; HSF1; HOXA5; FOS; ID4; SOX11; PIAS1; ZNF770; DNMT1; ZNF93; ZBTB17; ZNF611; ZNF264; HSF4; ZNF136; ZNF74; ZNF85; TULP3; ZNF500; PAX5; BRD4; MED15; ZHX2; CNBP; IRF9; CHD7; VPS72; FOXM1; NAB2; PBXIP1; HIRA; CREM; CIZ1; TOX3; LHX3; IRF6; ZNF257; SIX3; NR1H2; SOX9; FOXF1; ZNF711; XRCC6; TFAP2A; VGLL1; ZNF219; ZNF816; LDB1; SOX3; PROP1; HMGB1; ZNF415; CBX7; ARID1A; POU2AF1; TDP2; SRY; ZNF551; SKIL; PBX1; ZBTB44; ZNF253; EHMT2; ZSCAN9; CDK2; KLF13; REL; HIPK2; DEK; NR5A2; ZNF682; PAX6; PITX1; ZIC3; E4F1; THAP4; ZKSCAN1; SIN3B; ZNF141; NR2F1; TRPS1; MLXIP; CDX1; NEUROD1; CALR; PFDN5; FOXK2; JUP; HBP1; GATA6; ZNF768; ZNF571; THAP7; ZNF573; ZNF232; KAT2B; DDIT3; ID1; CAPN15; ZBTB16; ZNF239; ZNF195; NR4A3; BACH2; HHEX; SMARCB1; WT1; ZFPM2; PBX3; ZNF268; SOX17; PIAS4; ENY2; NR1H4; RFXANK; ZNF426; INSM1; PHF1; TOX; RAD21; TRIB3; ZFP36L2; PNRC1; OSR2; FOXF2; JUND; EN1; SSBP3; EHF; INSR; TCF25; E2F2; NR4A2; ABL1; ARNT2; HOXB5; KLF7; ZNF430; TP63; MYRF; DLX2; GLI3; TTF2; HIC2; LIN28A; CREG1; JUN; ELF5; TCF21; CEBPD; TFDP2; MYCL; EGR2; BNC2; CHD8; MTA1; MXI1; CNOT2; ZMIZ1; HES1; DLX5; EZH2; DACH1; E2F8; HDAC9; ARID5B; BCL11A; ID3; AEBP1; NR4A1; HOXB2; PSIP1; KDM5D; NR2F6
Down-regulation	198	PPARG; NCOR2; FHL2; TSC22D3; PDLIM1; SOX4; STAT1; HOXC6; CRK; XBP1; TAF1D; PSMD9; NUP62; MYC; KAT7; GABPB1; PPARGC1A; NFKB1; DNAJC1; TAF10; PIAS3; ELK1; PIR; SMAD2; TCERG1; PATZ1; TRIM16; ZBTB11; ING2; ERBB2; KDM2A; LOXL2; TBP; YBX1; RUNX1; HIPK3; HOXC10; ZFP64; LPIN2; MYCBP; HMG20A; PUF60; BCL3; PKNOX1; C1D; AHR; HR; NFE2L1; SMARCA4; SMARCE1; STAT3; BCLAF1; HDAC2; ZMYM2; TRIM32; SNW1; SREBF1; KDM5B; RNF14; UIMC1; KDM4A; BMI1; REST; USP22; FOXD1; USF2; POU5F1B; BRD8; RNF141; HNRNPD; RUVBL2; ZNF189; MEF2A; CUX1; PURA; NR2C1; RBM14; IKZF5; MED1; ERG; MSX1; CREB3L1; EDF1; MEF2C; HOXC13; DRAP1; HDAC7; MTDH; NFYC; DPF2; RBBP4; TADA3; HLTF; DDX5; CEBPZ; NFIL3; DR1; PIAS2; EED; NCOA6; PSPC1; UBP1; MAGED1; ARID4A; SMARCA5; CTR9; TRIM28; NCOA4; LIMD1; TAF7; MSC; HMGN3; RNF6; ZBTB1; PRRX1; NEDD8; SP100; ENO1; PHF2; ELK3; RBBP8; RNF4; CHD9; ZMIZ2; PBRM1; MYOD1; IRF7; MNAT1; ORC2; FOXE1; PCGF2; KLF2; ETS2; GTF3A; ITGB3BP; SIX1; TLE1; BAZ2B; HIVEP2; EPAS1; AFF1; TCFL5; YWHAB; ZBTB18; MED6; REPIN1; COPS2; CCNA2; PHF8; IRF4; PMS1; FOXJ3; RNF10; NPAS2; SUB1; POLR2A; IRX5; RNF111; SIM2; BASP1; MED7; CBX3; TRIM22; SFPQ; RFX5; NR2F2; MED23; CHD3; HDAC6; LZTS1; SAP30; BAZ1A; POU4F1; RB1; ZNF302; ASCL1; FOSB; SMARCA2; RBPMS; HSBP1; CRY1; BATF; FOXC1; JARID2; MBD2; LMCD1; NAB1; EGR3; TSC22D2; SP110; BATF3; PTRF; NR1H3; TRIM29; KLF4; EYA2; TRIP6; CEBPA