Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69936	Icariin	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	NR1H2; ILF2; KLF11; NANOG; NOC2L; CERS4; TBPL1; SOX2; HMGA1; PRDM14; ZNF331; GATA3; NFATC4; RUVBL1; FOXF1; CTNNB1; SPDEF; KLF6; ZNF274; MYBL1; HIRA; TAF1C; SALL2; E4F1; MLXIP; GRHL2; TULP3; CENPF; DNMT1; HIPK2; ACTL6A; NKX2-2; GMNN; BRD4; TFCP2; TP63; ZNF544; THAP7; RXRA; PCGF3; MNDA; ZXDC; ZNF665; ING4; LHX3; FOXM1; SIRT7; NR4A2; ZNF3; MYRF; ZNF74; CHD7; ISL1; ZNF350; MED15; CNOT3; WWP1; KDM5C; ZNF93; ZNF500; ZSCAN18; SMARCB1; INSM1; ZNF43; ZFP36L1; RAD21; IRF1; TCF25; LITAF; CNBP; TFAP2A; ENY2; NAB2; FOXG1; TCEA1; CDK9; PTTG1; NR4A3; FOXO3; SOX13; PSMC3; IRF6; ID4; XRCC6; TDP2; CDK2; VPS72; FOXJ1; JUND; ARNT2; MEIS2; TP53; MTA1; JUP; PBX1; SPIB; RORA; SOX9; SOX17; NFKBIA; ZNF264; KLF7; IL16; BRD2; EHF; TOX3; MAFF; ZFP36L2; KLF2; SSBP3; HHEX; ARID1A; IRF5; PAX5; ZNF266; NR4A1; DDIT3; FOXF2; ELF5; LIN28A; BNC2; ABL1; PAX6; ATF3; MYCL; ZNF423; HDAC9; NR5A2; TRPS1; EYA1; SOX11; DLX5; BHLHE41; ZNF91; TCF21; BTG1; HIC2; HMGB2; ARID5B; MAFB; ARNTL2; PSIP1; SMARCA1; TXNIP; NR2F6
Down-regulation	154	FHL2; PPARG; ERBB2; CDK8; NFAT5; STAT3; PSMD9; IKBKAP; SOX4; XBP1; NFE2L1; ING2; C1D; ZNF131; NR2C1; REST; TBX3; MYCBP; HOXC6; ZNF16; TLE4; HMG20A; CHD9; SMAD5; ZNF146; ZNF7; TSC22D3; NUP62; TEAD1; SP100; CCDC59; ZNF629; CHD1; ZNF267; SERTAD2; PURA; GABPB1; HOXC10; NFKB1; CREB3L2; NCOR2; ECD; DPF2; BCL10; BMI1; TSC22D1; TRIM16; PIAS3; BAZ2B; ENO1; MSC; IRF4; WNT4; ZBTB11; ZNF189; RNF10; ZBTB38; ZNF148; NCOA6; BTAF1; UBP1; EMX2; IRF7; AFF1; MEF2C; BRD8; RBM14; MYOD1; ZNF24; MED6; TCERG1; HIPK3; SMAD2; IRX5; ZNF292; SMARCD3; SIX1; PITX2; SNW1; MED7; CCNA2; ZNF652; TLE1; FOXN3; TMF1; CTR9; RUNX1; MSX1; TAF1D; TRIM22; HMGB3; NR2F2; CLOCK; BATF; RNF14; AHR; CUX1; PBRM1; NCOA4; ARID4A; RNF111; TFAM; YWHAB; HDAC6; HOXD3; TBL1X; ZNF443; ZBED2; ZBTB1; HOXB7; SNAI2; SMAD7; ZSCAN31; MEOX2; IRF2; RUNX3; KDM5D; VDR; ZEB2; RB1; MNAT1; MEF2A; MED1; SPEN; ID2; FOXJ3; DBP; NR1D2; BAZ1A; SMAD6; MAGED1; ZNF302; ING3; FOXD1; MDM2; MYT1L; BATF3; BBX; PTRF; MED13; HTATIP2; RBPMS; HOXB6; BASP1; CREG1; FOXC1; ESR1; TRIP6; NFE2; HMGN3; NRIP1; DACH1; TGFB1; ASCL1