Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69913	Ubenimex	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	NFKB2; PPARD; HOXA5; TBPL1; CHD7; SATB1; CERS4; GABPB1; MYBL1; HOXC4; ZBTB17; TOX4; PAX5; HDAC5; LITAF; ISL1; ARID4B; DDIT3; PSMC3; ARID3B; SSRP1; XRCC6; RERE; INSR; HHEX; CRYM; HEY1; POU2AF1; ETS2; PNRC1; ILF2; ESRRG; RORA; JUP; THAP10; HOXB7; RFX5; ZNF217; MEOX1; SMARCA4; CBX7; UBE2I; TAF10; SIX2; HLX; CUX2; RUVBL2; DNMT1; ABT1; POU4F1; PQBP1; TRIM16; HES1; TWIST1; SHOX2; ZBED1; TFAP2A; TCF7L1; MEIS2; ITGB3BP; FOXG1; MLXIP; PTTG1; FOXM1; HMGA1; FOXF2; PBX1; ZBTB18; ARNT2; PCGF2; JARID2; EDF1; HDAC1; CDC5L; NFE2L3; KLF7; HOXB6; PFDN5; ZNF423; VDR; LEF1; ERG; HOXB5; NKX2-1; BACH2; ST18; IRF1; AEBP1; TP63; HOXC6; RBPMS; TRIB3; HMGA2; HDAC4; SPEN; WWC1; HDAC9; INSM1; FOXC1; MECOM; PBX3; HDAC6; BCL11A; TLE1; HOXB2
Down-regulation	109	ERBB2; BIRC2; THAP11; ZZZ3; MYCBP; CD3D; ZNF148; HOXA10; TFEC; CHD9; UBP1; PURA; TSC22D4; CEBPD; BRD4; ELF2; BAZ2B; FLNA; REST; ZNF146; TRIM22; CREB1; STAT3; ETV1; ASH2L; SFPQ; CLOCK; AHR; TRIM28; RBL1; LPIN2; TCERG1; PEG3; PIAS3; KDM4C; HDAC2; ZNF175; TBL1XR1; ZBTB11; RUNX1; ONECUT2; ZNF83; CITED2; PEX2; AR; MED13; TGIF1; STAT1; BCLAF1; IRX5; NR1D2; NFYC; ZNF813; ERF; NFIL3; RUNX3; ZNF329; ZNF606; EHF; TBL1X; MAGED1; ZNF532; CCNA2; ING3; ESR1; MNDA; KLF6; ZFP36L2; PSIP1; NCOA1; TP53; ZEB2; HLTF; CERS6; BATF; BBX; ELF4; FOSB; WWTR1; HOXD3; EMX2; TRIM24; NFAT5; HMBOX1; SMARCD3; ZNF430; ZNF91; AFF1; MED1; KLF9; ZSCAN31; SMAD4; ASCL1; ID2; ZBTB20; TFAP2C; CREG1; SMARCA2; FOXL2; FOXJ3; SOX11; SUB1; KAT6B; NRIP1; NAB1; BAZ1A; TOB1; MXI1; KDM5D