Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69909	Dosulepin	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	ZNF586; KAT2B; GMNN; MYBL1; TCEA2; ZNF136; ZNF394; RRN3; ZNF180; ZNF274; DNMT1; TAL1; ZNF551; SSBP2; SALL1; CRYM; KLF11; POU2AF1; THAP10; SUPT4H1; TAF5L; NFE2L2; ZNF611; ERBB4; ZHX2; SSX1; ACTL6A; LHX2; ZNF329; THRA; CCDC59; ZNF160; CBX7; NCOA2; TAF5; ZNF331; ZNF107; WWP1; ZNF224; SP2; TGS1; TFAP2A; RAD21; PIAS1; ZNF264; TAF11; CTCF; ZNF721; PGR; ZNF652; ZNF268; ZNF467; MNDA; ZNF544; HIPK1; KLF1; RORA; ZNF235; PHF1; SALL2; TADA3; TEAD4; SP3; IRF9; ZFPM2; SP140L; ZNF134; CALCOCO1; PIAS4; RXRA; MEIS2; FOXM1; TDP2; FOXI1; AR; CD3D; KLF13; PBXIP1; ZNF492; RING1; ZNF573; ZFP36L2; ZNF12; SCAI; PRDM10; LITAF; MED21; ZNF623; VGLL1; CNOT6; REL; ZNF43; TCF7; GATA1; ZXDC; ZNF184; ZNF350; SOX17; INSM1; PCGF1; TERF1; LEF1; CDK2; ZNF423; ZNF529; ID4; ZNF44; CBX5; CREG1; TGFB1I1; TOPORS; GFI1B; TCF21; NCOA1; IFI16; OSR2; ZBTB20; NR1D2; ZSCAN18; NEUROD1; KLF2; NR4A2; CREBL2; NR3C2; CHD7; BBX; SMAD1; NR0B1; UBE3A; ZNF304; CITED1; ATF2; DDIT3; ARNT2; WT1; NR5A2; TCEA1; ESR1; NFE2; NFE2L3; NR2F1; NR4A1; HOXB5; PRDM1; DACH1; NFIC; IRF1; PSMC3; ZNF91; TP63; ZNF83; MYCL; HDAC4; MYCN; NKX3-1; PAX5; EHF; TRIB3; TRPS1; JUND; ZEB1; PSIP1; TFAP2C; ARID5B; BCL11A
Down-regulation	153	TRAK1; FLNA; SMARCE1; AATF; CRK; KDM2A; MYCBP; TAF10; HOXC6; RBBP4; POU3F2; STAT3; TAF1D; PSMD9; RUVBL2; PURA; TRIM28; YBX1; TBL1XR1; CARM1; TCERG1; PPARD; MEF2A; MTF1; SSRP1; GABPB1; SCAND1; USF2; ASXL1; PARP1; TP53; NEDD8; HIVEP2; SMARCD2; XBP1; STAT6; PATZ1; CBX6; GABPA; NUP62; TSC22D3; TOX4; ARID4A; SREBF1; USP16; RHOA; PREB; RNF14; ZNF24; PIAS2; LHX6; EGR4; SMARCA5; RUNX1; HDAC2; NFIL3; AFF1; NFKBIA; MAX; TBP; MED1; NR1H3; PHF20; POLR2A; ZNF248; ENO1; KDM5B; UBE2L3; POU2F2; YAF2; HMGB3; ID2; UBE2I; SAP30; C1QBP; ZNF22; MED15; MEF2C; CALR; DR1; MKL1; SATB2; PRPF6; HIPK3; MXD3; BTAF1; MNAT1; FOXC1; ELF1; ZFHX4; NCOA4; AIP; PUF60; CITED2; ZBTB1; ZNF189; ZNF205; EPAS1; KLF6; KMT2A; PMS1; MXD4; MAGED1; KLF4; HOXA1; ETS2; NRBF2; MLXIPL; BAZ1A; CCNA2; YAP1; RBM39; BATF; MBD2; DMTF1; ATF4; RNF141; HMGN3; FOSB; ZNF281; NFAT5; CXXC1; IRX5; SND1; MSX1; HSBP1; STAT5A; PCGF2; CNOT1; SPIB; SIX1; MECOM; CENPF; NAB1; SPEN; YWHAB; VPS72; RB1; TSC22D2; HOXB7; MTA1; MAF; EMX2; ASCL1; SMAD3; NFIB; HLTF; GATA6; TFDP1; ELK3; ZBTB18; CEBPA; ID1