Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69878	Clemastine	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	CTNNB1; CERS4; KLF11; NR0B1; MYBL1; MYT1; PBX1; STAT2; FOS; INSM1; MDM4; ZNF394; POU2AF1; NANOG; TFAP2A; ZFPM2; ZNF117; FOXE1; ZNF586; GMNN; WDR77; SOX18; ZBED2; NKX2-2; ACTL6A; ZNF224; BHLHE41; DNMT1; HOXD13; THAP10; BNC1; TCEA2; CDK2; TDP2; L3MBTL1; GRHL2; SALL2; PHF1; WT1; PEG3; SAP130; AEBP1; RBBP5; GTF2F1; SIX6; ERBB4; NEUROD1; TP63; ZNF652; ZNF611; VGLL1; ZNF551; ZNF544; ATN1; TLE2; SOX17; RNF138; ZNF623; ZNF136; TRIM16; E2F5; ARNT2; SOX3; ZNF440; RAD21; ZNF345; ST18; POU2F3; NFE2L3; PCGF1; ZNF423; INSR; REL; TAL1; ZIC3; AHR; ELF4; CITED1; ETV4; CTBP1; TEAD4; TEAD3; TCEA1; FOXI1; ID4; NR2F1; SP2; FOXA1; PRDM1; MEIS2; TRIB3; MNDA; TGFB1I1; MED14; JUP; ZHX2; PIAS4; ZNF667; RBFOX2; CDC5L; IRF1; THAP7; CERS6; IRF6; LITAF; ZNF264; CREG1; TCF21; NR5A2; ZNF721; ZNF573; TFAP2C; PHIP; LIN28A; SOX11; TOX; ATF3; NR3C2; HHEX; GFI1B; KLF10; FOXM1; MYCL; ZNF91; EHF; TFDP2; HOXD1; HDAC9; LEF1; FOXF2; ESR1; LMCD1; HES1; BCL11A; NFIB; MAFB; PAX6; DACH1; NKX3-1
Down-regulation	195	CDK7; TRAK1; NFKB1; TRIM28; CRK; KDM2A; FLNA; MYCBP; USP16; PDLIM1; KLF12; PURA; AATF; GABPB1; SCAND1; NCOR2; CITED2; MED1; TAF1D; PPARGC1A; RUVBL2; GABPA; SMARCE1; CREB3L2; YWHAB; STAT3; KLF6; RELB; TBP; EDF1; NCOA4; FOXD1; SKI; TAF10; RUNX1; BCL3; NUP62; TRIM32; CRYM; POU5F1B; UBP1; BASP1; NFIL3; ZNF672; TADA3; KDM4A; TAF9; BRD8; HOXA10; NRBF2; DNMT3B; ENO1; ARID4A; TBL1X; ZBTB48; CCNA2; BCLAF1; ZBTB43; SATB2; RBM14; BRPF1; ARNTL; KLF9; HNRNPD; YBX1; NEDD8; BRD4; BCL6; MEF2A; UBE2I; ZNF281; NR1I2; SLC2A4RG; SMAD2; HLF; NFATC1; HOXC6; ETS2; TCF20; HSBP1; YAP1; PIAS3; CBX6; TAF12; ORC2; GATA3; ID2; PBRM1; RNF14; TCF4; ZNF148; PEX2; NCOA6; XBP1; RBM39; TRIM22; USF2; HOXA5; SFPQ; POLR2A; PSPC1; SMARCA5; ETV1; PITX1; ASH2L; FOXO4; SMARCA4; ZBTB18; NPM1; NR2F2; ING3; EPAS1; BTG1; MYOD1; CBFB; BRD3; ATF7IP; ZMYND11; HDGF; ZNF22; SMAD4; HMGB3; MAGED1; RXRA; DPF2; TFAM; ZBTB38; MSX1; SETD2; PRRX2; ZBTB1; RBPJ; NLK; SND1; CHD1; HIPK3; IRF4; BTAF1; ZMIZ2; CXXC1; KDM5D; KMT2A; CTR9; C1QBP; RERE; ID3; NFAT5; NELFB; TLE1; IRX5; BTF3; CUX1; MXD4; ID1; TGIF1; CHD3; ATF1; HOXC10; SIAH2; EMX2; FOXJ3; AFF1; ELK3; ZNF33B; ABL1; SMAD3; TULP4; RB1; PLAGL1; TCF25; KLF2; HMGB1; NAB1; TCEB2; ZBED1; SIX1; ZEB2; MBD2; NR1D2; TWIST1; SMAD7; KLF4; SMARCA1; HDAC6; ZIC1; ZMIZ1; BATF; BMI1; MAF; TRIM29; STAT5A; TRPS1; HOXB2; TRIP6; SMARCA2