Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69846	Midostaurin	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	159	KLF11; GMNN; ZNF394; CBX7; ZNF136; KAT2B; NFIL3; JAK2; SSX1; POU2AF1; ITGB3BP; HOXA5; ZNF184; DNMT1; TSC22D3; ZNF180; MYBL1; HIRA; PGR; TAF5; TAF11; TAF4B; DEK; LITAF; TRIM33; PRDM4; ZFPM2; SETDB1; OSR2; CERS4; NEUROD1; THAP10; TDP2; CAMTA2; NFATC4; SRCAP; ZNF32; SHOX2; NFE2L2; ZNF74; ZNF224; GRHL2; TTF1; TCEA2; ZNF107; ZFP36L2; ZNF232; PIAS4; GTF2F1; ZKSCAN4; ZNF331; MNDA; HBP1; EZH1; ZNF274; PCGF1; FOXO1; THAP7; NR2F1; SCAI; ZNF273; ZSCAN9; ZIC3; BNC2; FOXM1; TFAP2A; ZNF264; ZNF83; RING1; CERS6; MAK; ZNF75D; INSM1; TAL1; CBX4; CIITA; ZHX2; CREBL2; L3MBTL1; TBX3; CTBP2; TRPS1; ZNF768; ZNF141; PNRC1; PRDM2; HIVEP1; TCF7L2; EHMT2; ZNF623; JUN; TFEC; ZBTB16; ZNF652; CREB3L2; ZNF45; ATF3; ABL1; MED15; KLF9; TULP3; IRF6; ISL1; PRDM1; TRIB3; KLF10; NKX2-1; REL; CBFA2T2; CDK2; RFC1; SFMBT1; EHF; RAD21; MXI1; ZNF12; ZMIZ1; ZNF423; ZNF43; COPS2; EMX2; ZNF33B; TERF1; FOXF2; ARNT2; LEF1; TFAP2C; TWIST1; HDAC4; HOXD1; POU4F1; NCOA2; MEIS2; ST18; GATA6; TFDP2; RBFOX2; ZSCAN31; NR3C2; ID4; WT1; NR4A2; ELF4; NFE2L3; IRF1; ZSCAN16; DAXX; MAFB; ZEB1; TCF21; JUP; ARID5B; AEBP1; MECOM; HHEX; ID1; PAX6; BHLHE41; ESR1
Down-regulation	149	PUF60; MYCBP; HNRNPD; NFKB1; SMARCC1; HDAC2; SMARCE1; PARP1; YBX1; BCLAF1; YWHAB; RBBP4; NKX2-2; ECD; ATF7IP; AATF; ERBB2; FHL2; FOSL1; GABPB1; TCF15; UBP1; HDAC7; KDM2A; TAF10; TRAK1; TP53; C1D; STAT1; STAT3; POU3F1; TSC22D2; GABPA; SFPQ; YAF2; HMG20A; RUNX3; MEF2C; CBFB; USP16; HDAC1; NUP62; RCOR1; APEX1; CARM1; GTF2A2; MSX1; TRIM32; MSC; USF2; BASP1; MAGED1; TSC22D4; ZSCAN18; HOXC6; ZNF587; ARID4B; SMARCD1; IRF4; EGR4; BRD4; SOX11; NR1I2; DNMT3B; RELB; IKBKAP; TFCP2; CCNE1; SMARCA5; TAF1D; PIAS2; TRIM28; SUZ12; IL16; TBL1X; SUB1; PEG3; KDM5B; DDX5; NCOA4; IRX5; NRBF2; CCNA2; MYOD1; WIZ; TFAM; HIVEP2; CHD1; HIPK3; EZH2; STAT6; RNF141; FLI1; POLR2A; MED1; SMAD2; OLIG2; HEY1; BCL11B; C1QBP; ENO1; BATF3; NFAT5; MYT1L; BATF; TRIM22; ARID4A; PRRX2; RARA; BAZ1A; FOXC1; KDM5D; FOXD1; FOXJ3; MYCN; LMCD1; SNAI2; CTR9; NPAS2; ZBTB38; SIX1; BRD3; ALX1; GATA4; SOHLH2; KMT2A; PBRM1; MNAT1; HMGB3; SMARCD3; SMAD4; ATF1; EYA1; KLF6; ZNF443; EGR3; BMI1; AFF1; HLTF; WWTR1; ZBTB18; HES1; HMGA2; HMGN3; SMARCA1; ASCL1; HOXB2; SPEN; SOX9