Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69764	Chlorthalidone	GSE92742	SKB	Human	24h	10uM	EID0379

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	SSBP2; ID4; SPDEF; MYBL1; TFAP2A; ERBB4; CERS4; ZNF117; ZNF586; HIRA; TAF5; ZNF136; KLF13; CDK8; CEBPG; TBX2; DNMT1; ZNF354A; TDP2; CHD7; PBX3; KLF11; SP140L; ZFPM2; CD3D; IRF9; ZNF180; TP73; PBX1; FOXK2; ZNF43; CTBP2; SOX3; TAF5L; MEIS2; DEK; CREB3; HMGXB4; ZNF350; HOXB5; ZBED4; WT1; GMNN; MED17; OSR2; ZNF665; THAP10; RAD21; VGLL1; ELF5; ELF4; ARNT2; ZBED2; CCNE1; ZNF74; ZNF573; PHF1; NAB2; NR2F1; SP100; GRHL2; HOXB6; RREB1; ETS1; TEAD3; CBX7; ZNF652; TCF7L2; SOX17; TCF21; PSMC3; VPS72; MKL2; ZSCAN18; CDK2; TAL1; MYB; NFE2L3; SHOX2; HOXB2; GATA6; POU2AF1; LEF1; PTTG1; RBBP8; CDC5L; MNDA; VDR; HIC2; FOXF2; WWC1; ZNF264; DACH1; MEIS1; KLF1; NFE2; PAX5; MYRF; NR4A2; CEBPA; RNF6; NR5A2; TFDP2; ZNF423; CITED1; ESR1; GATA1; MXI1; INSM1; ZEB1; HOXD1; KLF2; TTF2; EMX2; SOX11; DLX2; BNC2; SOHLH2; HDAC9; NKX2-1; HHEX; HLX; EHF; IRF6; ZNF331; AEBP1; NR4A1; HOXB7; ZFP36L2; LITAF; CSDE1; ZNF91; MYCL; CBFA2T3; TOX; BCL11A; EGR2; E2F8; HMGB2; BHLHE41; ATF3; ID1
Down-regulation	138	TBL1XR1; SMARCE1; BHLHE40; KLF12; TRAK1; STAT3; ZNF384; DNAJC1; TAF1D; NCOR2; POU5F1B; MED1; BCL6; PPARGC1A; CRK; HIPK3; KDM2A; NFKB1; HOXC6; NEDD8; ZNF226; TCERG1; MEF2A; PRMT2; GTF2I; RUNX1; BCL3; TAF10; BCLAF1; NUP62; YBX3; BMI1; EDF1; RBBP4; YBX1; AATF; APEX1; TBP; MYC; TAF9B; SMARCD2; TSC22D3; TRIM28; RUVBL2; TP53; TCF15; UBP1; HSF2; SLC2A4RG; KAT7; ORC2; HLF; PURA; SREBF1; SMAD2; TSC22D1; STAT5B; BRPF1; ENO1; RNF141; HIVEP2; ZMIZ2; PIAS3; YWHAB; MLLT10; FOXO4; EP400; TSC22D2; ZFHX4; MSX1; PITX1; PIAS2; ETV1; SUV39H1; ERF; TBL1X; KDM5D; TRIB3; BRD2; POLR2A; REST; CLOCK; MXD4; BRD8; KMT2A; MEF2C; MAF; KLF6; RFX7; ELK3; FOXO3; DPF2; HSBP1; NR2F2; LZTS1; HMBOX1; STAT1; DMTF1; IRF4; CEBPD; ZNF516; MED23; NCOA1; ZMYND11; TCF4; CRY1; MAFB; NFAT5; HOXC10; SIX1; FOXJ3; TRIM29; ING3; CTR9; TCF12; BATF; CNOT1; BTG1; ZIC1; MAGED1; NFKBIA; TXNIP; HLTF; ZEB2; ZMIZ1; IRX5; DNMT3B; NAB1; SUB1; FOXD1; TGFB1I1; SMARCA2; POU4F1; RFX5; WWTR1; HDAC6; ZBTB18; NKX3-1