Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69717	Diltiazem	GSE92742	PHH	Human	24h	10uM	EID0377

Response Information :

Types	Number	Response transcription factors
Up-regulation	169	GATA3; NCOA4; KLF2; CRY1; CREG1; MEOX1; MAFB; MAF; TBP; RCOR1; NPM1; ZEB2; BIRC2; REST; ZNF146; KAT5; NRBF2; CCNC; ORC2; EZH2; RBBP4; BCL11B; REPIN1; MED6; MED1; ZNF226; NFIB; TRIM16; ZNF12; NEDD8; RUVBL2; TSC22D1; ZBTB14; HLF; ZNF302; MNDA; RNF141; TBPL1; SAP30; MAX; ZNF184; CENPB; TRIP6; KAT7; ARID4A; TAF12; CERS6; TBL1X; PBRM1; BCL6; DNAJC1; APEX1; MYCBP; ZNF148; SMARCE1; ZNF32; HLTF; HMG20B; ZNF3; RYBP; DPF2; PLAGL1; RFX5; NR3C2; USF2; DR1; ZNF467; DRAP1; ZFHX4; TFEC; C1D; ITGB3BP; ZNF536; TTF1; C1QBP; NKX3-1; ZNF23; REL; USP22; SSX1; MGA; RNF10; THAP10; KLF5; MED7; TCF7L2; HMGB1; HOXB7; NR1D2; NRIP1; SMAD6; TBL1XR1; TRIM28; EGR3; CHD1; PNRC1; SP3; CCNA2; DDX5; BAZ1B; NR4A3; HBP1; CEBPG; BRD2; MTF2; HSF2; BRD8; RBPMS; ENY2; PTTG1; PSPC1; RHOA; SAP18; CEBPA; ATF1; SREBF1; ENO1; E2F3; CITED2; ISL1; ZBTB38; PHF20; ZNF22; ZMYND11; DEK; TBX3; BBX; BHLHE41; ID2; FOSL2; ELK3; SMAD3; ZNF217; FLNA; EMX2; NFAT5; NR1H2; EGR2; SATB1; BAZ1A; POU2AF1; POU4F1; PUF60; BAZ2B; GATA2; MTDH; TLE4; ZBTB20; HMGN3; SCAND1; BASP1; IKBKAP; HHEX; TGIF1; TSC22D2; CARHSP1; ABL1; TXNIP; TRIM29; TWIST1; TFAP2C; NFKBIA; TLE1; SFPQ; HTATIP2; ID1; SOX11; VGLL4; SOX9
Down-regulation	146	PDLIM1; AFF3; SUZ12; IRF6; PKNOX2; LHX2; ALX4; LHX3; EMX1; TULP3; POU6F1; GATA1; ZSCAN18; FOXL2; TEAD4; SERTAD2; AEBP1; RFX2; TCF21; KLF13; PBX3; SOX21; GATA4; CSDC2; TP73; BARX2; ZNF324; CITED1; ZMYND8; SPDEF; ESRRG; GATA6; OVOL1; VGLL1; MAPK8IP1; FEV; CDIP1; ZNF556; CDX1; YBX3; KLF15; HOXC5; HMBOX1; E4F1; THRB; EZH1; ZNF232; NR2F1; TFAP2A; NEUROD1; ASCL1; POU2F2; EP400; DMRT1; ELK4; ATN1; ZNF264; TGIF2; MEIS2; HOXA11; SNAPC4; ACTL6B; NCOA1; ZNF177; ZNF444; NR2E1; CEBPD; SOX13; CSDE1; RUNX1; BLM; WNT4; ARID3B; ZNF589; ZNF211; PKNOX1; NFIX; WDR77; HOXB5; MLXIP; ID4; MEIS1; OLIG2; PHF1; FOXA2; PGR; TFCP2L1; TRIM24; BNC1; NCOA6; TTF2; SIAH2; CDK2; NFATC4; SP100; MKL2; NPAS2; FOSB; ZNF580; FOXF2; BATF3; ZNF331; BCL11A; ZNF43; MECOM; ZNF652; CUX2; RBL2; ZNF544; MED21; KLF6; KDM5C; LITAF; FOXF1; SOX2; NFE2L3; ZNF587; BRD4; ZNF606; NFATC3; CRYM; ELF4; WT1; ZNF91; ZBTB18; ERG; WWTR1; RUNX3; CREB3L1; INSR; FOXD1; KLF9; IRF9; JUN; CREB1; IFI16; ZFP36L2; HOXB2; ZNF131; SSBP2; INSM1; SOX17; ZNF586; ZIC1; STAT1; ZMIZ1