Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69699	Cdk2-5-inhibitor	GSE92742	PHH	Human	24h	10uM	EID0377

Response Information :

Types	Number	Response transcription factors
Up-regulation	126	TCFL5; SOX4; KLF2; PATZ1; PIAS2; HMGB2; SATB2; HIRA; REPIN1; MNAT1; RBBP4; MLLT10; SMAD4; TFDP2; ARNT; RUNX1; RFC1; ZNF764; TRIM29; MYB; ZFHX4; ZNF3; PLAGL2; WIZ; NEUROD1; PMS1; USP21; NR3C2; LEF1; ZBTB14; MECP2; KAT5; E2F5; MGA; JUND; BTG1; ZNF302; ZNF576; THAP7; MEF2A; SOX5; NCOR1; HDAC4; MED6; DRAP1; ZEB2; SIX1; CTBP1; TBL1XR1; TOB1; TCEA1; EZH2; NHLH2; INSM1; CLOCK; KAT6B; FOSB; CBX7; TOX; CERS6; SMAD7; MED4; MAML1; MYCBP; ERBB2; CHD7; GTF2IRD1; USP22; FOXO4; RXRA; MAX; NRBF2; ZNF212; KDM5D; TCF4; DR1; ZNF423; URI1; KLF11; CBFA2T3; PCGF3; CTBP2; DMTF1; FOXN3; FOXG1; SCAND1; PRKDC; FOXA1; NFATC3; ENY2; ID3; NRIP1; RFX5; PAX6; CHD8; CEBPG; ZIC1; SLC2A4RG; TSC22D1; TOPORS; PEX2; FOXF1; E2F3; PUF60; ZBTB20; PSIP1; CCNA2; SAP30; MEIS2; IRF8; CBX3; MTF2; TLE4; POU4F1; ASCL1; HLTF; DACH1; ZMIZ1; ATF3; MNDA; ZFPM2; LOXL2; TP63; ID1; ID2; NR1H2
Down-regulation	93	ZNF813; TCF25; KAT2A; NFKB1; ZNF331; ENO1; CBFB; ZNF665; ZBED2; ZNF91; HOXB2; ELF1; TCERG1; BATF; TCEA2; SP100; CENPF; RXRG; CCNT1; STAT3; ZNF83; MAFF; PQBP1; NFKBIA; ZNF667; ZNF611; LITAF; PTRF; TBX2; SMARCC1; ZNF165; FOSL1; ZNF350; EHF; ZNF177; CERS4; RYBP; HOXB6; SOX17; HOXD1; ZNF224; CALR; IFI16; BCL3; RNF6; NR2F2; ZNF512B; TCF7; FOXC1; CREB5; ELF5; SSBP2; LMCD1; ELF3; ZSCAN18; ZNF415; TBPL1; ZNF432; TWIST1; ZNF43; ZNF131; ZNF606; EPAS1; ZNF544; HOXB5; TBL1X; PEG3; SREBF2; RERE; KLF9; SAP18; STAT6; ZNF580; ZNF134; KDM5C; BRD4; PLAG1; TRPS1; ZNF22; TXNIP; ZNF586; PIR; EGR2; ZNF589; NFAT5; ZMYM2; TFEC; PBX3; ELK3; CRYM; ID4; HEY1; AHR