Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69591	Midostaurin	GSE92742	PHH	Human	24h	10uM	EID0377

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	NR2F2; PSMD9; TSC22D3; SIX2; KAT5; GTF2A1; CREG1; PMF1; MYCN; ING4; PCGF1; UIMC1; SETD3; MLX; CCNE1; DPF2; RHOA; KLF6; RELA; ZFHX3; CEBPD; KLF2; LITAF; CREB3; MXD4; TSC22D1; TGFB1I1; FOXO3; POLR3F; MXI1; JUND; ZNF593; THRAP3; WHSC1; NKX3-1; RELB; SLC2A4RG; PARP1; PRDM4; ERBB2; PAX8; RNF10; RFX5; TSG101; SALL1; VPS72; ACTL6A; FOXJ3; HDGF; BIRC2; MECOM; MED24; YEATS2; PSIP1; TRIM29; IRF9; ATF5; CUX2; SIX1; EYA2; ZFP36L2; ZNF516; CD3D; ARID1A; DRAP1; MSX1; HMGB1; CUX1; KAT6B; EMX2; ABL1; KDM5D; MAZ; APEX1; MITF; MYBL1; GATA2; NFATC3; NFAT5; BAZ2B; URI1; SMAD1; PDLIM1; OSR2; PPARGC1A; CEBPG; NFIC; ZNF32; TLE1; SOX17; ETV5; KMT2A; ESR1; CBFB; TAF1D; ZNF512B; TBX3; CITED1; SPEN; NEDD8; SALL2; NFIB; PSPC1; NFKBIA; MLXIP; SSBP2; HTATIP2; JUN; TRIP6; INSR; NR1H2; TXNIP; IRF7; ZBTB16; ID2; GTF3A; IFI16; ID1; BHLHE41; ATF3; ZMIZ1
Down-regulation	132	HMGB2; CHD1; UBE3A; EGR4; EGR3; ZEB2; HIPK1; KLF13; HIC2; ING2; ZFPM2; PITX2; TGIF1; TERF1; RNF138; XRCC6; ARID4A; SMARCA5; MAX; ZNF165; HLX; CAMTA2; IKBKAP; PAX6; PAXBP1; BRD4; USP22; IRF4; USP16; COPS2; MAF; NFYB; ETS2; NLK; SUPT3H; GATA6; NR4A3; ZBED4; CHD7; RNF6; ZNF665; NR4A2; HIF1A; FOXF2; ZNF573; TOX3; VDR; ATF7IP; ENY2; HIRA; CHD4; TSC22D2; MYT1L; ZNF177; AEBP1; BCOR; ZBTB1; ZZZ3; BCL10; CCNA2; ZBED2; CDX1; TRIM24; MEOX2; HDAC2; PNRC1; HIPK3; CITED2; GLI2; EZH2; CDC5L; INSM1; CDK8; SIAH2; LIMD1; ZMYND8; TULP4; ZNF331; TFAM; CDK9; CREB1; FOXG1; NCOA2; ZFP30; NR4A1; DR1; ZNF711; LEF1; IRF8; ELF5; NR2F1; NR1H3; EN1; TRPS1; ASXL1; BASP1; TFAP2A; DDX17; DNAJC2; SSX1; AHR; NANOG; SAP30; SUZ12; TOX; PAWR; SATB2; SFPQ; RLF; RNF111; TBX2; EHF; PLAGL1; TAF9B; FOXD1; DACH1; ZNF131; SOX11; CBX4; SOX10; ZNF589; KLF5; EGR2; TOB1; GTF2I; TCF21; NRIP1; ZIC1; SHOX2; TFEC; TCF4; FOSL2