Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69574	Roscovitine	GSE92742	PHH	Human	24h	10uM	EID0377

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	MNAT1; KLF5; RNF138; IL16; KAT6B; SP140; PATZ1; REPIN1; HLF; LEF1; FLNA; NKX3-1; VDR; PEX2; ZNF467; EZH2; CERS6; ARNTL; LPIN2; TRIP4; UBE3A; SP140L; UBE2B; BCL3; SMARCE1; NR3C2; KLF2; SSX1; TRAK1; ING2; CCNA2; TRPS1; DR1; ZZZ3; GRHL2; ID1; SREBF1; RYBP; MECP2; HBP1; RUVBL2; SMAD4; HIRA; SP110; BRD8; NR4A3; C1QBP; NKX2-1; NR4A1; ELF1; BTAF1; USP22; CHD1; MYCBP; MED4; RCOR3; ASH2L; NR2F2; TSC22D1; ZKSCAN1; SP100; DMTF1; ORC2; SMARCA5; YAF2; NCOA2; ZBED1; NRBF2; FOXF1; STAT4; NRIP1; CREM; ZEB2; TRIM22; ID3; VEZF1; CTNNB1; LOXL2; TFCP2; MTF2; TRIP6; FOXA1; ENY2; TCEA1; TFAP2A; SERTAD2; CCNC; HDAC1; PTTG1; JUND; TBL1XR1; CBX3; TBX3; STAT6; SATB1; HLTF; CDK2; PUF60; HEY1; SNAI2; RAD21; PTRF; RUNX3; NFIB; NR4A2; HMGN3; CREB3L1; NR2F1; KLF9; TRIM29; NR1H2; SFPQ; JUNB; ATF4; ZMIZ1; PAX5; WWTR1; ATF3; TLE1
Down-regulation	99	ZKSCAN7; YBX3; MYCN; NHLH2; RBFOX2; CEBPD; CRY1; ZNF175; ZNF443; CUX2; ZNF91; AGO2; HOXB6; ZNF93; ZNF232; ZNF117; TAL1; IRF5; ACTL6A; ZFP69B; EHF; MAGED1; ZIC3; HDAC9; POU2F2; ZNF593; MSC; ZIC1; CITED1; LHX3; CREB5; ZNF562; ZNF43; ZNF573; HOXA11; ACTL6B; PKNOX1; ZNF85; SIM1; NKX2-2; LIN28A; POU5F1B; SMARCA1; ENO1; ERBB4; RBL2; RERE; TAF4; SREBF2; CTR9; NFE2L3; HES1; HOXB2; CDK8; ZNF189; MYBL1; ARID5B; ZNF239; SMAD1; ZNF606; TCEB2; SSBP2; JUN; ZNF544; MYT1L; PCGF1; ZNF329; EMX2; TOX3; SMARCA2; YBX1; CEBPB; ZBTB16; AR; NAB1; ZNF654; ERG; HMGB1; WT1; RXRA; ZHX2; SHOX2; SPEN; PSIP1; ELK3; KAT2B; CRYM; RLF; INSR; SOX17; ZNF264; PBX3; RORA; MKL2; GATA2; STAT1; ESR1; KDM5D; MEIS1