Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69475	Mdm2-inhibitor	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	85	SHOX2; ZNF274; HOXB2; ESR1; CHD7; PHF1; BNC2; PBX2; TCF3; PKNOX1; ZSCAN18; ZNF587; HLX; ZEB1; FOXL2; HOXB5; TCF21; RARA; PSPC1; TRIP4; HOXA11; JUND; ATF3; HOXB6; MSC; PRMT2; NFE2L2; PSIP1; BRD7; SETD3; HOXA10; PAXBP1; GLI2; TRIP6; SOX17; NFX1; ELK4; FOXD1; HDGF; CDK8; GATA6; FOS; SOX13; INSR; RNF4; FOSL2; SATB2; HOXD1; BATF3; SF1; SREBF2; OLIG2; NHLH1; PLAG1; BAZ2B; ENO1; IRF9; IFI16; ZNF217; FOXF1; NFIC; RBL2; MEIS1; HDAC2; ATF6; MYBL1; OSR2; PBX3; KLF7; ID4; DNMT1; EMX2; EYA2; MEIS2; TCEA2; ABL1; SP100; WT1; TCERG1; WWTR1; NR2F1; NR2F2; ZBTB18; PEG3; TRIB3
Down-regulation	62	EZH2; CCNA2; MTF2; TSC22D1; ENY2; USP22; KDM4A; NR1H3; SAP30; NR0B1; DNMT3B; NR2C2; ARNTL; NPAS2; NRIP1; NANOG; ZNF267; MYT1L; CERS6; MAX; KLF5; MYT1; RBBP4; ING2; NFIB; SIX1; NFE2; SMARCA5; ZNF273; PURA; RFX7; HOXA1; HIRA; BHLHE41; SFPQ; ZNF146; PIAS2; PIAS3; MYCBP; KAT8; UBE2B; ZNF165; ZBED2; MEF2C; BIRC2; WWC1; MAFB; RNF141; CARHSP1; TOX; BCL11B; RORA; PTTG1; ID2; RFX5; GATA2; KAT6B; KDM5D; LEF1; LOXL2; SOX9; FLNA