Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69469	Leflunomide	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	201	HOXD3; ZSCAN32; PIAS4; ESR1; INSR; RARA; BHLHE40; HOXA11; SMAD6; CUX2; ZNF629; IKZF1; RNF4; SIRT2; EP300; PIAS1; BACH1; TAF9; HOXC8; BTF3; ARID4B; ATF5; NRL; SIAH2; MECP2; NFKB2; DBP; CHD9; HDAC3; PPARG; WHSC1; ATN1; ZNF217; CDYL; CUX1; SMARCA4; NFIC; BRIP1; PRMT2; SETD3; HOXC5; PSPC1; PKNOX1; BRD3; TBX21; ZNF281; CREB1; SOX17; MEF2D; SERTAD2; ZNF556; HHEX; ZFP36L1; FOXC1; KLF7; ZNF358; BCL11A; TXNIP; DMTF1; YWHAB; GTF3A; THAP10; GRHL2; MTA1; HDAC11; ZBTB44; MAFG; KLF12; ZNF710; MXD4; HOXC4; CARM1; PHOX2A; BATF; LHX3; HOXB6; FOXD1; BPTF; FOXN3; GATA6; ETV5; SATB1; SNAI1; SUPT4H1; TCF3; MYBL1; DACH1; SAP130; ZBTB39; CREG1; RFC1; MECOM; ZNF7; DAXX; ZNF771; CAMTA1; RFX2; MYB; PRDM1; ZNF510; PARP1; BLM; NR0B1; AFF1; RXRA; NFATC3; SOX4; ZNF423; ETS1; SSBP3; KAT2B; ZKSCAN1; CHD1; BANP; ZNF184; ZNF587; HOXA10; TGIF2; XBP1; IKBKAP; RFX5; MYCN; TBX2; PSMC3IP; MEIS1; STAT3; AGO2; IRF6; SMAD2; PAX6; ZNF189; FOXF1; HDGF; NR2F2; FOXO3; ZNF239; ZNF131; ESRRG; HR; TRIP4; CEBPA; ZNF75D; ERBB4; NCOA3; MYC; HNRNPD; CBFA2T3; MEN1; SIX1; ZNF443; WT1; SSBP2; SOX2; REL; ZNF516; SIM2; TRIM24; HOXC6; TBL1X; CBX2; ERF; SALL1; NHLH1; SMAD1; SP3; CHD7; PEX14; MEF2A; PLAG1; ZNF91; IRF9; HAND1; LITAF; ELF4; TAF9B; ENO1; TRIM32; ZNF175; RREB1; ELF1; SMAD3; RBL2; GATA2; MEIS2; ZHX2; DLX2; NAB2; ZNF623; LMCD1; MNDA; ZNF589; JUP; PBX1; ZMIZ1; NR2F1; TCEA2; BASP1; ZBTB18; SOX9; NR2F6; TRIB3
Down-regulation	169	MTF2; CCNA2; EZH2; MITF; INSM1; TP63; YBX3; HIF1A; C1QBP; ID1; USP22; SOX15; VDR; CCDC59; TFEC; MYCBP; DRAP1; SREBF1; AIP; GTF2A1; TFAM; CBX7; SNAI2; EGR4; SSRP1; ENY2; TCF20; TSC22D1; ZNF432; DNMT3B; CXXC1; CHD8; ID3; ZNF10; TRIM22; SIX6; FEZF2; MDM4; PRKDC; SSX1; ZNF460; MDM2; NR1H3; NFE2L2; ATF3; CEBPG; HDAC9; DEK; NCOR1; SMARCA2; MAFF; TMF1; FOXO4; CBFB; KAT6A; XRCC6; ZBTB20; PBRM1; FOSB; ATF1; ZNF23; NFE2; ASCL1; KLF5; ZNF692; ILF2; BMI1; ZNF529; PEG3; BAZ2A; FOXG1; MAK; HLF; PTTG1; ZNF544; NFIB; NFAT5; BIRC2; NCOA2; ZNF155; EHF; GMNN; ASH2L; SPIB; SMARCD3; PNRC1; EED; NR2E1; TRIM29; FOXN2; ACTL6A; ZNF331; RUVBL2; MYT1L; MTDH; TOB1; IFI16; CRY1; EN1; TGFB1; TCEA1; SIX2; PRRX1; ZSCAN18; ZNF83; POU2AF1; ZNF551; CNOT1; ZFPM2; LIN28A; HCFC2; ST18; SALL2; ZNF415; CBX6; MED1; PHF8; HLTF; JUNB; JUN; HOXA5; SIM1; SP100; ZFP36L2; CEBPD; FOS; ANKRD1; EGR2; CRK; HEY1; RHOA; YBX1; NR4A1; CREBL2; KDM2A; JUND; HMGB1; WWTR1; TAF7; ZBED2; TOX3; MBD2; MEF2C; KMT2B; USF2; RBPJ; ABL1; PAX5; STAT6; ZNF165; RNF138; PSIP1; MAF; BRD2; ZNF532; BAZ1A; MAFB; RBPMS; AHR; AEBP1; NR1D2; ERG; ID2; ELF5; TCF4; NR1H2; HES1; FOXO1; KLF4