Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69458	Purmorphamine	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	TCF3; ZBTB24; HOXB2; PIAS4; VDR; SP140L; CDK9; KLF13; NFE2L2; IRF6; TGIF2; DACH1; RBBP8; POU2AF1; FOXC1; ZNF239; HLX; SMARCD1; NOC2L; TLE2; PIAS1; BAZ2B; ESR1; ERCC3; CARM1; SMARCC1; HOXB6; DBP; GTF3A; SFMBT1; BNC1; MYBL1; RUVBL1; WNT4; RNF6; ZBED2; TCF7L1; MKL2; TCF21; FLI1; TRIP4; FOXI1; TERF2; ARID5B; HOXC10; ZNF557; CHD7; SNAI1; BNC2; JUP; FOXL2; TFAP2A; CDK8; NFE2L3; PMS1; MXI1; ZNF556; NFATC1; HOXC4; SHOX2; HHEX; NFIC; EYA2; NCOA1; OVOL2; PSPC1; ERBB4; RFX2; NKX2-1; NR4A2; NR2F1; NHLH1; GRHL2; MYCL; CTBP2; IRF9; TFAP2C; ELF3; BACH2; EYA1; BCL11A; ZSCAN18; FOXG1; HDGF; CBFA2T2; ID4; DLX2; RBL2; TAL1; HTATIP2; KLF9; TBX3; IFI16; CRYM; HMGA2; DAXX; TGFB1I1; SOHLH2; GATA6; STAT1; CREB3L2; MEIS2; PSMC3; SOX9; NR2F2; SP140; TCEA2; ZNF512B; CEBPD; WWC1; MNDA; WWTR1; HES1; SCAND1; PBX3; ELF5; KLF2; TRIB3
Down-regulation	141	EZH2; CCNA2; HIF1A; CERS6; RYBP; MTF2; CNBP; ENY2; DNMT3B; DEK; MYCBP; IKBKAP; CTNNB1; C1QBP; POU5F1B; BMI1; MED13; SMARCE1; MTF1; ETS2; DDX5; BBX; PRRX1; HLF; NRIP1; KLF10; ZNF146; SAP18; SAP30; NCOR1; USP22; ZNF302; NR2C1; DRAP1; JARID2; ARID4A; NR1D2; ZNF665; KLF3; TSC22D2; HMBOX1; TBL1XR1; ZNF12; MSX1; PHF8; LPIN2; NEDD8; CAPN15; MED6; NCOA4; SPIB; ZNF248; BTG1; KDM5D; ZIC1; SATB2; HDAC9; CBFB; ZNF529; MTDH; AFF1; PURA; VGLL4; VEZF1; NR3C2; ZBTB1; XBP1; ZBTB38; ATF1; ZNF721; ZNF23; TMF1; BIRC2; FOXA2; BRD8; PBRM1; E2F3; MBD4; ZNF160; PTTG1; RUVBL2; MLXIP; HSBP1; SFPQ; NRBF2; USF2; ZNF329; PNRC1; STAT5A; EED; RBM14; TRIM22; KDM2A; SMAD1; REPIN1; NFAT5; TWIST1; UBE2B; RBPJ; ID2; ZNF468; MYT1L; PIAS2; MED1; ZNF415; PDLIM1; UBP1; SOX10; TAF1D; HDAC2; HIPK1; NFKBIA; TOX3; HEY1; SMAD7; HAND1; KLF4; TCF7; BASP1; ZBTB20; TP53; EGR3; TLE1; RORA; BRD2; ZEB2; EHF; ZMIZ1; ID1; MAF; ABL1; HLTF; LEF1; GATA2; TCERG1; MECOM; SPEN; CD3D; EMX2; ZBTB18; PEG3