Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69453	Pnu-120596	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	IRF6; CUX2; ELK4; TEAD3; TCF7L1; HOXD3; FOXI1; TLX1; VDR; PIAS4; EMX1; HCFC1; ZNF671; MED14; ZNF154; MECP2; PRDM10; RCOR3; NPAS2; GRHL2; SOX18; NRF1; MYBL2; SERTAD2; LHX3; HOXC5; NCOA1; NOC2L; NCOA6; BRWD1; HOXC4; FOXM1; PAX6; REL; CHD2; PHF1; ZNF75D; EP400; SALL2; MAFF; SOX3; MYCL; SALL1; CBX5; ZNF350; ASH1L; KLF9; FUBP1; SAP130; PRDM14; LHX2; EYA2; STAT4; PGR; BAZ2A; BCL11A; SMARCA1; SOX13; CNOT6; DLX2; JUN; HMGB3; MXI1; HOXB5; ZNF394; UBE2L3; NR4A3; FOXL2; GFI1; NHLH1; BCL11B; ZNF43; ZNF91; CREM; SOHLH2; LHX6; ZEB1; ZSCAN18; DBP; USP21; FOXN3; YEATS2; SHOX2; TFAP2C; ZNF74; SOX17; ZNF107; ESR1; PBXIP1; ARID1A; MYBL1; HDGF; FOSB; LMCD1; HOXA11; HIRA; GLI2; TGIF2; EPAS1; HMGB2; HOXB6; PBX1; HOXA1; DACH1; HEY2; ZNF589; SIAH2; ZNF239; NAB2; ZNF423; MKL1; MKL2; GMNN; ZNF83; ZNF232; OLIG2; PBX3; NR5A2; SIX1; HDAC4; ESRRG; CENPF; JAK2; INSR; HLX; CD3D; TAL1; FOXG1; WNT4; ZNF117; CBFA2T3; DLX5; RBBP8; OSR2; ABL1; FOXO1; CDK2; TFDP2; SPDEF; FOS; ERG; DDX17; HSF1; HOXB2; PLAG1; NKX2-1; DNMT1; TCF21; PKNOX2; BACH2; SSBP2; TCF7L2; POU4F1; ID4; ZNF512B; NFE2L3; TCEA2; PSMC3; NCOA3; ERBB4; AEBP1; IRF9; ZNF331; RBL2; TULP3; SPEN; MEIS2; NR4A2; NKX3-1; SCAND1; JUP; MYB; NR2F6; TRIB3
Down-regulation	149	CDK7; MTF2; TSC22D1; XBP1; MYCBP; EZH2; IKBKAP; CCNA2; USP22; HIF1A; SMARCA5; PIR; THAP1; ZBTB38; DR1; COPS2; DDX5; E2F5; MED7; CERS6; ZNF146; ATF2; REPIN1; ZFHX4; BRD8; FOXJ3; ZNF460; MYC; TCF12; ADNP; MED6; NR1I2; ZZZ3; TAF9; VGLL4; AFF4; MEIS1; NPM1; ZNF576; TLE1; ZNF12; NFIL3; PCBD1; TFAM; HDAC6; ZBTB1; BBX; NFAT5; VEZF1; MED4; TEAD1; ZNF148; KDM5D; RYBP; RUVBL2; MDM2; MITF; SMARCE1; TSC22D3; SNIP1; TAF10; TOB1; EHF; BMI1; TRIM16; MED21; TAF7; WWC1; HLF; JUNB; CTR9; HCFC2; ENY2; MNAT1; CREG1; BRD4; MTDH; CCNC; ZNF443; BIRC2; NRIP1; PCGF1; ETS2; PTRF; NR1H2; ZBTB43; TRIP6; ATF1; NCOA4; TRIM28; CEBPZ; KLF2; CRK; ZNF14; CHD1; UBP1; ZNF23; CREBL2; SIX2; RBPMS; YBX1; PEX2; NRBF2; CRY1; TRIM29; YWHAB; GTF2IRD1; EGR2; DRAP1; BAZ1B; HAND1; IRF8; ASCL1; CREB5; HOXA7; SMARCD3; MBD2; TRIM32; TOX3; RBM14; UBE2B; KLF4; COPS5; FOXF1; FOSL2; FHL2; DNAJC1; HMGN3; ELK3; ISL1; KAT6B; ZBED1; IL16; BASP1; BCL3; WT1; CEBPD; CITED2; NR1D2; PPARG; ERBB2; ZBTB18; ZNF652; PTTG1; MECOM; PLAGL1; HLTF; GABPB1; SMAD7