Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69445	Ponalrestat	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	160	TSC22D3; IKZF1; ZSCAN18; ZNF580; SMARCC1; POU2AF1; SMARCC2; BRD4; FOXK2; BAZ2A; CBX5; IRF6; GLI2; TCF7L1; SSX1; THRA; CDIP1; MED24; TCF3; ZNF492; RERE; PRDM1; ZNF350; ZIC3; ZNF135; ID4; PAX5; BACH1; ADNP; JUN; BCOR; CHD7; STAT4; CNOT3; LDB1; MEOX2; SALL1; RARA; SIX3; SKI; CNOT6; ZNF536; HIVEP1; SMARCD1; CIITA; EP300; ZNF432; TP63; KLF9; YEATS4; SPIB; CBX4; ZNF354A; CREB3L2; MEOX1; ANKRD1; BACH2; PGR; HOXD11; SERTAD2; SRF; IRF4; NEUROD1; NFATC3; FOXJ3; ZNF345; MTDH; MTA1; KLF13; CRY1; ZNF556; TERF1; ZNF257; RBL2; CCNT1; PBX2; TTF2; TULP4; L3MBTL1; ZNF529; MYCL; SLC2A4RG; TRAK1; ZNF34; TCF7L2; BBX; SALL2; MYBL1; HOXA11; HMGB2; ZNF329; MED1; SOX17; SOHLH2; GRHL2; WWP1; SIX1; ZNF551; ASCL1; RAD21; TXNIP; TRIM22; RLF; CITED1; ABL1; EZH1; ZBTB16; ZNF589; JUP; RBBP8; SOX10; CERS4; EN1; PSIP1; TCF21; NCOA1; TAL1; NCOA2; MXD1; SP140; PTTG1; MNDA; CBFA2T2; ZNF217; SMAD7; WT1; NKX2-1; ZBED2; BCL11A; TCERG1; SOX11; HSF1; MYCN; MEIS2; FOXO1; DAXX; NAB2; ERBB4; OSR2; PEG3; LITAF; ZNF264; TOX; SPDEF; ZNF623; PBX3; TOX3; SOX9; GATA6; STAT1; HES1; BTG1; RUNX3; ST18; WWTR1; GATA2; DLX2; TCEA2; KLF2; TRIB3
Down-regulation	118	VDR; SREBF1; MEIS1; NONO; ZFHX4; MED6; EWSR1; XBP1; TBPL1; CXXC1; ETV5; MLX; RUNX1; HDAC7; BRF2; COPS2; AIP; HOXB7; ZBED1; SNW1; DDX5; TWIST1; CBX3; ZNF384; ESR1; SMAD1; NFX1; RUVBL2; SNIP1; NCOA4; ZNF410; ZBTB1; ARNTL; CREB3; TRIM16; MECOM; TCF4; HMGB3; PIAS3; EDF1; ZNF552; PDLIM1; PRRX1; RBBP4; ASH2L; MED23; SATB2; SMARCA5; HDAC1; KMT5A; HDAC5; TAF12; RBBP5; USF2; NFIB; ZNF273; SFPQ; SATB1; ID2; YBX1; EPAS1; ZNF672; TRIP6; CEBPA; SMARCD2; DRAP1; MITF; ATF4; ELK1; RBPMS; USP22; RNF14; LOXL2; NR5A2; HOXA7; CCNA2; NFKBIA; ENO1; FOSL2; DACH1; HOXA5; MYT1L; NCOR2; COPS5; MEF2A; CBX6; CARHSP1; MAF; CEBPD; PIAS2; APEX1; TBX2; MBD2; MKL2; TRIM32; CREB3L1; MEF2C; ZIC1; TBL1X; CCNC; NFKB1; DDX17; TSC22D2; TFAP2C; NKX3-1; KLF6; KAT6B; ERG; CREG1; SOX4; BIRC2; ZMIZ1; PPARG; BCL3; NR4A2; SCAND1; EMX2; KLF4