Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69403	Alprostadil	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	171	SOX2; PAX8; ZEB1; HOXD3; TCF7L1; HOXB5; SOX21; HOXB2; BRD3; SIX3; LHX3; OVOL1; ARL2BP; RXRA; IRF6; MED25; BARX1; ZNF711; CUX2; CDIP1; NFE2; E2F5; POU5F1B; MYBL1; FEZF2; EMX1; HOXD1; TP73; HOXB6; HOXC4; ZNF154; ZNF117; PRDM14; TEAD4; SETDB1; BNC1; PROP1; TCF21; ZIC3; FOXL2; ZNF202; UBE2L3; WT1; AR; NFE2L2; FOSL1; MKL2; PRDM1; TGIF2; ID4; ACTL6B; SOX17; TBX21; LIN28A; CEBPE; NFATC3; DACH1; PGR; THRB; ZNF768; ESR1; CEBPD; ZSCAN18; FOXC1; ZFP36L1; RARA; BACH2; ARID5B; SOX13; JUND; PKNOX2; HDGF; TCFL5; STAT4; NR5A2; TBX19; ZNF43; SALL2; TFAP2C; OLIG2; EPAS1; VPS72; ZNF467; EHMT2; RBL2; BCL11A; MYCL; SNAI1; PBX3; ZNF500; LITAF; ZFP36L2; POU2F2; PRDM10; ZNF133; LMCD1; ZNF74; TERF2; PMS1; NAB1; PEG3; MXI1; TRPS1; SOX3; PBX1; FOXA2; SOX11; KLF9; CHD3; SF1; ZNF85; CHD7; GFI1; CENPF; KAT2A; ZMIZ1; ASCL1; ZNF91; BNC2; FOSB; ELF4; YAP1; ZNF232; CHD9; NKX2-2; NCOA1; CBFA2T3; SPDEF; DLX2; RFXANK; PAXBP1; EMX2; HDAC4; IRF9; NFATC4; HIRA; KLF5; ZNF22; MYRF; SMARCA1; KLF6; TULP3; PHIP; TCF7L2; DDX17; ERBB4; TAL1; MECOM; KLF11; RUNX3; WNT4; MEIS2; MYCN; NAB2; PLAG1; MNDA; TCEA2; IRF1; NR2F1; SOHLH2; RHOA; ZNF623; CALR; ID1; LOXL2; BCL3; HOXA5; ID3; KLF4; ZNF589; TRIB3
Down-regulation	183	CDK7; MTF2; EZH2; USP22; NRIP1; MED4; CCNA2; PIR; ELF2; C1D; MYCBP; XBP1; IKBKAP; MED7; ATF5; CTR9; TRIM22; SNIP1; CBX7; SAP30; CBX3; AATF; NCOR1; CERS6; ITGB3BP; MITF; PCBD1; ZFP30; DDX5; HMG20B; MED6; RNF6; BBX; CCDC59; TSC22D1; PPARGC1A; ZBTB38; SREBF1; NFYB; THAP1; CHD1; BCL10; ARNTL; ZNF468; CRK; SMARCA4; RBBP7; ING1; TMF1; SMARCA5; NPAS2; HLF; SP2; DDX54; NR1D2; DR1; BHLHE41; MED23; TSG101; FOXO4; ZNF274; GTF3A; TOPORS; ZZZ3; NEDD8; MDM2; SMARCE1; COPS2; KDM5D; ENY2; LPIN2; MED24; REPIN1; CLOCK; C1QBP; TAF9; FOXJ3; BCOR; PHF8; ADNP; RBBP4; MBD2; USP16; UBE2B; ZNF443; ING2; SOX15; ZMYND8; TRIM16; ARID4A; NR2C1; ZNF14; HCFC2; E2F2; EGR2; SNW1; SFPQ; ZNF148; MED1; TAF10; MED21; ZNF146; ORC2; ETV5; EGR3; CRYM; ETS2; ZNF12; PRRX1; SAFB2; NR4A1; ZBTB20; CREBL2; NRBF2; BMI1; KAT7; SAP18; PIAS2; ASH2L; RBBP5; ZNF329; CNOT2; BAZ1B; MLXIP; UBP1; ING3; ZBTB18; KLF2; ATF1; HNRNPD; RBPMS; PSMC3IP; ZNF226; ZNF432; ZNF44; TOB1; CEBPZ; PQBP1; ZNF23; ZBTB11; ZNF281; TRIM28; DNAJC2; AFF1; IRF2; GABPB1; TSC22D2; USF2; FOXD1; NFAT5; HTATIP2; ISL1; CRY1; NKX3-1; ERBB2; RUVBL2; DNAJC1; TRIP6; NR3C2; SSX1; ID2; MAGED1; ZNF430; HAND1; RNF10; ZMYM2; KAT6B; TLE1; WWC1; RBM14; MAF; NR1H2; MTA1; MAZ; LEF1; YBX1; BIRC2; SOX9; NCOA4; POU2AF1; PLAGL1; HLTF; PPARG