Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69362	Dextromethorphan	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	KDM5A; HMGA2; BBX; NFAT5; SUPT3H; SOX21; ARID5A; PITX2; ZNF124; ING4; MED15; E2F3; MYBL1; KLF9; TCFL5; FOXD1; SIX3; INSM1; TAF1; TP63; BNC1; KLF3; STAT4; ZIC1; FOXC1; CCNT1; TBX21; NEUROD1; HOXC10; HDGF; HOXD1; BATF; GLI2; ARNTL2; RORA; RSF1; IRF6; HMGA1; HIVEP2; VGLL1; PFDN5; SOX5; ZNF22; PLAG1; NR1D2; VPS72; BAZ2A; SOX10; THAP7; CAMTA2; KLF13; HIC2; TCF7L1; ZNF721; TBL1XR1; ERBB2; ZNF33B; ZNF32; ENO1; SMAD6; PAX6; ZNF711; ZNF224; SKI; RUNX1; TULP3; ZNF165; ZBTB20; TRPS1; ZNF292; SMAD5; GATAD2A; RLF; CEBPD; SALL2; YBX1; HOXB2; FUBP1; ZHX2; NFATC4; ZNF91; RXRA; FHL2; ATF6; NKX2-1; AGO2; SMARCA1; DDIT3; ZNF160; HOXB6; EGR3; RBL2; ELF4; TCEA1; DDX17; PHIP; SOHLH2; ZNF175; CREB3L2; HSF1; BTG1; FOXN3; TRIM29; ZNF232; ZNF264; TXNIP; RUNX3; ERBB4; DLX2; STAT1; SOX9; HOXA5; ZNF589; TRIB3
Down-regulation	111	MLX; ARID4B; VDR; CBX3; ZFHX4; CDK9; MLXIP; AEBP1; MEIS1; PIR; CTR9; TOB1; TCF12; NFE2L2; SMARCA4; SUPT4H1; MTDH; BRD8; ZNF281; MITF; ISL1; TWIST1; YWHAB; CUX2; ESR1; CTCF; RBPMS; TSC22D1; BMI1; NFYB; ADNP; SP3; SOX15; MAF; PRRX1; ID1; BAZ1A; TOX3; RNF6; SHOX2; MED23; WT1; THAP10; SAFB2; RBBP8; MED24; ELF3; ETS2; WWP1; IKBKAP; HLX; MXD1; NCOR2; KLF6; TLE1; TBPL1; PPARGC1A; RB1; MYBL2; TBL1X; TAF10; PHOX2B; ASCL1; GTF2A2; EGR2; MECOM; OSR2; FOSL1; UBP1; HDAC4; SATB2; HTATIP2; FOS; ASH2L; NR4A1; PITX1; PAXBP1; HAND1; HOXB13; LEF1; HDAC1; ZNF423; HDAC2; PBX1; PTRF; SMAD1; KAT6B; PSMC3; KLF4; TRIM16; RNF10; CDK2; TCERG1; CITED2; EMX2; FLNA; POU2AF1; SOX17; ZFPM2; TRIM28; BIRC2; HES1; MAFB; CREG1; PAX5; ZMIZ1; BRD2; BHLHE41; RFX5; MSX1; KDM5D