Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69348	Midostaurin	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	159	HOXA10; ESR1; SHOX2; ZNF671; BRD3; HOXB5; IRF6; CUX2; EVX1; PIAS4; KAT2B; HDGF; TLX1; NOC2L; HOXA6; JUND; PHF1; TLE2; SSRP1; HINFP; LITAF; ZFP36L2; ZNF688; SERTAD2; NRF1; MXI1; ZNF91; ZNF274; TCF7L1; E4F1; SIRT2; MED16; LHX2; HOXC4; SIX5; TAF5; ZNF358; FOXD1; HOXB6; HOXA11; CCNE1; HMX1; HOXA4; MYOG; NCOA1; WHSC1; ZNF224; CARM1; ELK4; FOXC1; HIVEP2; AES; RBL2; ZSCAN18; SETD3; BNC1; MSC; PRMT2; PDLIM1; CDIP1; AFF1; PBX3; HOXB2; TCF7; BANP; FOXN3; ZNF544; ABL1; RING1; FOXO3; ZNF512B; HMG20B; ID4; PIAS3; PBXIP1; SSBP3; ZNF93; SALL1; ZNF83; CALCOCO1; CEBPD; EZH1; HLX; STAT4; RFXANK; SOX17; ZNF556; ZFX; RELB; ZNF500; JUP; PGR; MLXIP; MED24; ZNF133; PBX1; ZNF350; HBP1; PPRC1; TCF15; DRAP1; GFI1B; TULP3; RXRA; ZNF562; TAL1; RHOA; GMNN; ZEB1; FHL2; PSMC3; IRF5; NR5A2; CALR; DBP; SCMH1; BATF3; LMCD1; CREB5; IRF9; NFIC; TWIST1; TBX3; CITED1; EN1; DDX17; DNMT1; NCOA2; PLAG1; HOXA5; RUNX1; KLF7; ZNF217; BCL11A; RBPMS; ZNF721; MYCL; ZNF160; OSR2; CD3D; MYBL1; TCEA2; ZNF331; EYA2; INSR; AEBP1; SCAND1; HOXC6; STAT1; GATA6; RUNX3; SOX9; BHLHE41; HES1; DLX2; MYCN; NR2F2; NR2F6; TRIB3
Down-regulation	145	EZH2; CCNA2; SAP30; MTF2; TRIM22; DR1; USP22; C1QBP; ENY2; SMARCA5; MYCBP; ITGB3BP; XBP1; ING2; IKBKAP; EGR3; ZZZ3; SFPQ; NRIP1; ELF2; USP16; NR4A1; MED4; PLAGL2; ASH2L; HLF; NR1H3; ZBTB1; C1D; CCDC59; KLF5; COPS2; ZNF146; MED7; ZNF33B; EGR2; SSX1; ARNTL; CHD1; KDM5D; TOX3; MED21; NCOA4; KLF4; PHF8; UBE2B; MBD2; TOB1; FOXO4; TBL1XR1; MTDH; ADNP; ZNF124; DACH1; HMGA1; RBFOX2; RNF111; FOXA1; ETS2; SMARCD3; HIC2; UBP1; ZSCAN31; ARNTL2; RNF6; CHD4; MYRF; MAX; KLF10; JUNB; NR0B1; ZNF23; SOX10; CCNC; ATF4; DNAJC2; TGIF1; VEZF1; ATF7IP; NR2F1; YWHAB; RAN; MYT1L; TRIM16; RBM14; PIAS2; TAF11; CEBPA; ATF3; WWC1; FOSL2; ERF; PRRX1; ZNF195; ANKRD1; BASP1; PAX5; INSM1; GTF2I; ZFPM2; ASCL1; MEF2C; EHF; NANOG; TSC22D2; SMAD4; REPIN1; RNF138; ZNF165; FOSB; NFAT5; HEY1; RNF14; MECOM; HMGB2; RORA; YBX1; ERBB2; ID1; IRF8; PTTG1; TULP4; LOXL2; PLAGL1; FOXF2; NKX3-1; KLF2; TRIM28; SOX4; ID3; GATA2; ZNF532; RFX5; NR4A2; MNDA; ZBTB38; CBX6; SMAD1; GABPB1; ZMIZ1; ELF5; MAFB; HLTF; PPARG; ZEB2