Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69329	Roscovitine	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	164	NR3C1; GATA3; VDR; DACH1; IRF6; NFE2L2; TAF5L; SHOX2; RARA; CHD7; IRX5; ETS1; TCF7L1; BRD3; SETD2; HOXB5; LHX3; MYBL1; KDM5C; RERE; TCF3; HOXC5; GATA6; ZBTB17; MXI1; FOXC1; CREM; TP63; CUX2; E4F1; TERF2; HOXB6; HOXA11; CTCF; ARID3B; MBD1; BRD7; RUVBL1; IRF9; HOXC4; FOXD1; TBX21; DLX2; CDIP1; TGIF2; BANP; IFI16; TFAP2A; TAF4; PRDM12; GRHL2; MED14; EMX1; CNOT6; SETD3; SMARCA1; ZNF580; RBM39; PCGF3; PRDM10; SERTAD2; DBP; CCNE1; HOXC13; SOX13; PRDM5; ZNF117; SUPT5H; TRIM25; NR4A3; CBFA2T3; SRF; POU2F2; ZFP36L2; NFATC3; NR2F1; HOXB2; EHMT1; NFKBIB; MECP2; ARID5B; RFX2; SOX3; CTBP2; ID4; JUND; BACH2; VGLL1; EP400; NHLH1; RXRA; CERS4; ERBB4; ZNF24; CAMTA1; PHIP; NR5A2; DDX17; EP300; PEX14; OSR2; SOX11; FUBP1; HDGF; TFDP1; PBX3; ZNF512B; RBL2; CENPF; FOXM1; NCOA6; GTF2A2; IRF7; ZFP36L1; IRF5; STAT1; MAML1; NCOA1; NAB2; TBX2; HBP1; TBX3; PAXBP1; PPRC1; IRF2; ZMYND11; WDR77; RAD21; PAWR; ZNF91; FOXO1; HEY2; JUP; HEY1; REL; TCF7; KLF9; SMAD4; CREB3L2; SOX17; SPDEF; LMCD1; TULP4; ZNF232; MEIS2; TCEA2; ZNF93; SMAD3; TRPS1; EYA2; TCF7L2; CD3D; ELF5; FOXF1; TLE4; SPEN; ZNF589; BASP1; PAX5; HES1; HMGB2; RUNX3; SOX9; TRIB3
Down-regulation	156	MTF2; ELF2; MYCBP; TSC22D1; CCNA2; MITF; NRIP1; PCBD1; EZH2; USP22; C1QBP; CRK; MED7; NR1H4; SREBF1; FOXO4; TFEC; NR1H3; ETV5; ZNF146; NEDD8; CBX7; ATF4; TRIP6; RUVBL2; NFIB; ZNF302; PATZ1; MED4; ARID5A; DRAP1; HLF; NR2C1; ZNF3; C1D; YBX3; CBX6; HMGA1; BCL10; HOXD10; KDM5D; TBL1XR1; HTATIP2; KAT8; PA2G4; RYBP; ID2; YWHAB; MDM2; KMT2A; ZNF544; ZMYND8; TFAM; HCFC2; MED6; BRD8; ZFHX4; PIR; TRIM16; ARID4A; SOX12; TOPORS; ZBTB16; CENPB; BBX; TSC22D3; NFAT5; TFE3; DEK; E2F3; RBBP4; NCOR2; ZNF646; USF2; HDAC7; MYC; ZNF384; TRIM28; KMT5A; ASH2L; NR4A1; BIRC2; ZBTB7A; ZNF12; CAPN15; IKBKAP; ING3; TCF20; DNAJC1; TOB1; NR3C2; MGA; ING2; ZNF148; PQBP1; EMX2; DNAJC2; ZNF23; HOXA7; MAX; COPS2; FLNA; ZKSCAN1; PHF8; COPS5; MEF2C; MED1; KAT6B; ZNF329; KAT6A; TGFB1; WWC1; ZMYM2; EHF; ZNF415; ZNF468; ZBTB20; PTRF; ID1; NR1D2; MAF; TLE1; FOSL2; NKX2-2; PRKDC; UBP1; TBL1X; REPIN1; RBPMS; NFE2L3; BRD2; ZNF32; PLAGL1; MTA1; TP53; ABL1; PITX1; RNF14; CARHSP1; YBX1; ATF3; BAZ1A; HOXA5; CALR; PTTG1; ZBTB38; NR1H2; PPARG; KLF2; NKX3-1; HLTF; BHLHE41; LEF1; KLF4; ST18; PEG3