Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69291	Reboxetine	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	164	NFATC3; HOXD3; TSC22D3; CUX2; HHEX; OSR2; SSX1; BHLHE40; HOXC4; SAP30; HOXB6; CDK9; NFE2; HOXA11; HOXC8; ESR1; SIAH2; RXRG; RARG; KLF13; EP400; PAXBP1; MYF6; ZBTB40; LHX3; FOXN3; MTA1; MYBL1; DBP; TCF7L1; E4F1; POU2F1; MECP2; ZNF350; IRF9; PAX6; EMX1; TGIF2; SHOX2; ZNF202; UIMC1; CTCF; HOXC6; ZBTB17; HOXC11; WNT4; RARB; CIZ1; LMCD1; HOXC13; SAP130; KAT2B; SIM2; RERE; IRF7; POU4F1; DLX5; PCGF3; CERS4; PRDM10; PCGF2; TOX4; ATN1; KDM5A; KLF6; STAT1; SNAI1; PAWR; EP300; TFAP2A; ERBB2; BACH2; NFE2L3; PBX1; SMARCD1; GTF3A; MEN1; HEY2; HOXB7; NCOA6; KLF1; NFIC; TERF2; SERTAD2; SATB1; PSIP1; HNRNPD; HMBOX1; EHMT1; ZNF556; DAXX; ANKRD1; MSX1; SF1; WDR77; CITED2; BCL11A; TRRAP; RFX2; SOX3; HMGB2; BNC2; ARID5B; MKL2; NKX2-1; SOX17; GATA6; HMGN3; NCOA1; SSBP3; ZSCAN31; IRF8; MYCL; BARX1; ZNF589; SCMH1; CDC5L; HOXB13; FOXC1; DLX2; SOHLH2; KLF9; CENPF; APEX1; RREB1; SPEN; EN1; CHD7; FUBP1; SMAD4; TCF7; MNDA; HDGF; DDX17; ERBB4; SOX9; CBFA2T3; MAGED1; ZFHX3; CREB3L2; HIRA; MYRF; TFAP2C; CDK2; INSR; PHIP; SCAND1; NR1H2; MEIS2; AEBP1; RFX5; IFI16; PSMC3; GATA2; WWTR1; ID3; NR2F1; SOX11; TCEA2; NR2F2; POU2AF1; KLF2; PBX3; TRIB3
Down-regulation	177	USP22; CCNA2; MTF2; MYCBP; EZH2; HIF1A; CERS6; MAFF; MED4; LPIN2; THAP1; ENY2; EGR4; C1D; TOB1; RYBP; ZNF267; ARID5A; FOXO4; ELF2; ZNF148; ZBED4; ZIC1; CNBP; MED7; ZNF576; TFAM; UBE3A; TOPORS; SOX15; DEK; BCL6; XBP1; NR1I2; CREBL2; TMF1; ZFP30; NR1H3; INSM1; TBPL1; ATF2; EHF; ZNF165; NR4A3; BRD8; ZNF329; ING3; MED21; TLE1; TBL1XR1; E2F3; ZNF302; ZBTB38; REST; CRK; BBX; ARID4A; LZTS1; MLXIPL; MED13; SKI; ADNP; ZNF12; MITF; MYNN; BIRC2; RNF111; BRD2; ZNF468; PURA; PBRM1; ZNF146; MED23; PEX2; CRY1; ATF1; ZSCAN12; DNMT3B; BRD4; MEIS1; SIX2; DRAP1; CBFB; SNAI2; HSBP1; ASH2L; PHF8; BCOR; NCOR1; FOXN2; NFAT5; BAZ1A; AHR; NR1D2; RUNX1; BMI1; ZNF23; KAT6A; TCF20; UBE2B; TBP; BTG1; TRIM29; ETV5; ZNF136; PROX1; ZBTB1; SMARCD3; MYT1L; PQBP1; ZNF273; BASP1; EGR3; TOX3; ZBTB20; IRF2; ACTL6A; PFDN5; ZNF160; ZNF529; ZNF44; ZNF721; EED; SAP18; PLAGL1; CEBPG; ZNF430; NRBF2; PDLIM1; ELK1; NRIP1; RELA; ZNF14; KAT2A; HMGA1; HLTF; KLF5; SMAD7; MTDH; ZNF611; SMARCA2; BHLHE41; FOXA1; EGR2; KDM5D; RRN3; ZNF264; TOX; ZBTB7A; TFCP2L1; CBX6; RUVBL2; ZKSCAN1; KMT2B; RBM14; TERF1; MAF; BCL3; HLF; JARID2; ZMIZ1; LITAF; USF2; CITED1; TP53; MAZ; ZBTB18; WT1; HDAC9; ZEB2; ZNF331; ETV1; PRKDC; TRIM16; ATF3; TSC22D2; HES1