Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69274	Chlorthalidone	GSE92742	PHH	Human	24h	10uM	EID0378

Response Information :

Types	Number	Response transcription factors
Up-regulation	209	DMTF1; HOXC10; MNAT1; RELB; TCFL5; IRF6; RBM39; VDR; MED17; TRPS1; SIRT2; CTBP2; NFATC4; OLIG2; CCNH; NCOA1; POLR3C; HOXC4; PITX2; CDIP1; E4F1; ZNF124; MYBL1; GLI1; KDM5C; MLXIP; HOXA3; BNC2; TCF3; HMGB3; BRCA2; SPIB; NEUROD2; FUBP1; TEAD4; ZNF85; KLF13; JUN; GATA4; ZNF556; TEAD3; PHF1; TGIF2; HOXC11; E2F5; CCNT1; SMARCD1; PLAGL2; MKL2; DACH1; ZNF117; TCF7L1; PRDM2; FLI1; PHIP; IRF5; NRF1; CLOCK; HOXA11; ING4; TRIM29; PAWR; SPI1; ZSCAN18; AEBP1; ESR1; SRCAP; SSBP3; TXNIP; RXRA; MYBL2; CNOT3; CHD7; RUVBL1; MYF6; TTF2; NR3C2; BAZ2A; CAMTA2; BNC1; PHF20; PIAS3; NPAT; VPS72; HOXC13; ASH1L; BACH2; STAT4; PGR; EZH1; ZNF91; TAF1D; THRA; CDK2; FOXI1; RARA; PRDM1; TULP3; SMAD1; PBX3; ZNF250; MAFB; FOXJ1; FOXL2; TP63; HMGB1; SPDEF; ZMYND11; HDGF; TULP4; ZIC1; SLC2A4RG; CUX1; ZNF266; FOXE1; YAP1; CUX2; PROX1; SMAD2; RBL2; HES1; HIVEP2; ZNF557; CBFA2T2; NKX2-1; OSR2; WDR77; ZNF430; CEBPD; SOX2; ZNF107; EN1; SMARCC2; PAX5; TOB1; ARID5B; RBBP8; ZNF354A; KLF5; SOHLH2; ERBB4; HSBP1; TERF2; ZNF224; ZBTB16; ACTL6A; ZMIZ1; CALR; THAP7; GFI1; FOXG1; TCF4; RERE; HLX; LITAF; TRIM22; NAB2; SSX1; BARX1; FOXO1; ZFP36L2; KLF9; MED13; ANKRD1; ZSCAN16; STAT1; ZNF195; PAXBP1; RAD21; POU4F1; BRIP1; TERF1; MYB; RFXANK; CBFA2T3; POU2AF1; NEUROD1; GATA6; ELF5; NFE2L3; GTF2A2; HOXC6; MEOX1; IRF9; SMARCA1; DLX2; SNAI2; ADRB2; NFIC; PBX1; ZNF467; TBX3; TLE4; ZNF232; PEG3; BTG1; CREB3L2; DNMT1; WT1; E2F8; TCF7L2; SSBP2; STAT6; LMCD1; HMGB2; NR1H2; SMAD7; ELK3; TRIB3
Down-regulation	219	C1QBP; TSC22D1; TCEB2; ZNF528; MYCBP; C1D; TRIP6; ASH2L; HTATIP2; CBX3; NFKBIA; COPS2; ETV5; ENY2; PIR; HEY1; RBPMS; APEX1; MTDH; HOXB7; MAFF; DRAP1; SAFB2; SETD2; ATF3; CRK; PDLIM1; SMARCA4; ZNF146; TOX4; MITF; PCBD1; TBPL1; DR1; PRRX2; BMI1; ZNF552; BBX; FOSB; MED24; RBBP5; GTF3A; ZNF274; RUVBL2; AHR; USP22; ZNF468; PSMD9; ZFP30; EZH2; SMARCA5; ADNP2; TBP; NR1H3; WWC1; RXRG; CCNA2; CREG1; ATF2; ZNF84; HCFC2; IKBKAP; NCOA4; ZNF302; NEDD8; CEBPA; ZNF593; SMARCC1; NR4A1; ZNF23; BRPF1; SUB1; CCNE1; PIAS2; FOXO4; IRF8; ID2; ZFHX4; TFDP2; NR1H4; DNAJC1; SAP18; FHL2; ZSCAN12; SP2; NONO; LZTS1; ENO1; HMGXB4; HMGA1; ZNF551; TRIM28; RLF; KAT5; RBBP4; HMBOX1; MYRF; BCOR; ETS1; TRIM16; CIZ1; UBP1; USF2; KDM5D; BCL10; NUP62; TAF11; BRF2; NFYC; ZNF134; KDM2A; SF1; HSF2; ATF4; ZNF329; KAT7; UBE2I; BIRC2; KLF10; NKX3-1; DDX17; CCNC; EDF1; HLF; KLF1; SUV39H1; PHF8; BAZ1B; RBBP7; SP3; SMAD6; CBFB; ZMYM2; ZNF304; ABL1; RYBP; SOX9; ERBB2; CARHSP1; HAND1; KLF6; DPF2; FOSL1; IRF1; PTTG1; MECOM; TP53; ZNF711; ORC2; CITED1; NFIL3; MYC; RNF10; ZNF264; RNF4; PTRF; RAN; CEBPZ; MAX; PHOX2B; VGLL4; HOXD1; BRD4; RHOA; ZNF672; EYA1; SMARCA2; CITED2; EGR3; FOS; ZBTB20; TGIF1; BAZ1A; JARID2; HLTF; TBX2; NCOR2; ZNF131; HOXA5; KAT6B; SFPQ; ETS2; TSC22D2; YBX1; HOXA7; RBM14; FOXF2; NELFB; SIX2; REPIN1; TAF10; ISL1; FLNA; TFDP1; HNRNPD; SMAD3; STAT5A; BCL3; SOX11; TLE1; ZNF532; SPEN; ZBED1; GABPB1; PSIP1; KLF4; PLAGL1; ZNF423; TOX3; HDAC9; ZNF652; ZEB2; RUNX3; TCERG1; MAF; ZNF586; ID1; MEIS2; BASP1