Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69232	Mdm2-inhibitor	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	188	HSBP1; PRKDC; MYC; TP53; REPIN1; BATF; TRIM32; HABP4; ELF1; ING3; ELK3; BRD2; SP110; EED; ZNF189; ZNF410; ZNF783; SND1; TCF12; RUVBL2; EGR1; CTNNB1; DNMT3B; HIVEP2; TLE2; MAFG; TBP; ZMIZ2; AFF1; MED27; NR3C2; CRK; PHF8; RXRB; TRIM27; PBRM1; ORC2; NFKB1; CDYL; LPIN2; CDX2; BLM; MYCBP; PDLIM1; POLR2A; TBL1XR1; ZNF23; GTF3A; BRPF1; MED1; RHOA; SOX4; BCLAF1; BMI1; CRY1; NUP62; NFIB; MEF2C; KLF2; GABPB1; BCL3; ZNF593; ZNF721; TFCP2L1; DNAJC1; EDF1; NPM1; SFMBT1; KMT2A; RBBP4; MTDH; NCOA4; BRD8; HLF; PURA; STAT5B; NR1D2; YBX1; RLF; SMAD2; HCFC2; XBP1; PCGF2; PA2G4; SOX15; TCF15; SETD3; HOXA5; TSC22D2; SNW1; HLTF; JARID2; CEBPA; ASH2L; ZFP36L2; MEOX2; BANP; BAZ1A; ZBTB40; NR1I2; NRIP1; JUND; DAXX; ZNF226; FHL2; CREB5; HTATIP2; GTF2IRD1; AATF; PARP1; MYT1; DPF2; CTR9; MAFF; TRIP4; MLXIP; SATB2; NFAT5; DDX5; TAF1D; KAT7; SREBF1; ATF1; ZNF267; PTTG1; ZNF430; ZBTB38; BHLHE40; DDX54; DEK; RBM14; ZNF160; ZEB2; TRRAP; CERS6; SMARCE1; TRIP6; EGR3; CCNA2; NFKBIA; NFIL3; SCAND1; PPARGC1A; NFKB2; MYT1L; BATF3; EZH2; SMARCA2; ZNF536; TRIM28; ENY2; DNAJC2; IKBKAP; ZNF146; PAX8; MED24; HDAC7; YWHAB; TSC22D4; MAGED1; MAF; NEDD8; ERBB2; RB1; MECOM; FOSB; TOX3; TCF4; SMARCA4; STAT5A; NRBF2; ZIC1; HIPK3; SATB1; KAT6B; TLE1; SMAD1; DRAP1; ZMIZ1; BASP1; TWIST1; ABL1; RBPMS; KDM5D; MSX1; THAP11; EMX2; HES1
Down-regulation	165	SPDEF; DNMT1; TFAP2A; HOXB6; NR2F1; PSMC3IP; ZIC3; INSM1; ZNF200; ATN1; ID4; MYCL; HOXB5; TTF2; MED14; FOXL2; ZNF557; CDK9; GFI1; HHEX; PAX4; CIITA; DLX2; TCF21; CDK2; ZNF623; YBX3; E2F8; ARL2BP; TEAD4; NEUROG2; MYBL1; NAB2; ZFP36L1; ZNF232; CREB3; NEUROD1; EHF; DCC; TCEA2; WT1; FOXE1; WDR77; ZNF770; OSR2; PLAG1; CSDC2; BACH1; ZFP69B; TFCP2; FUBP1; ZNF107; TBX21; PBX1; MEIS2; PAWR; SOX17; CTBP2; ZNF174; SHOX2; HOXB2; ZNF117; ZNF586; ZBTB6; ZNF835; NFE2; SOX18; ANKRD1; TFDP1; FOXF2; IRF6; ZNF141; VGLL1; PCGF3; EYA2; MED17; CITED2; ZBTB44; TOPORS; ZKSCAN8; MYBL2; ID1; ZFPM2; RBFOX2; ATF5; GLI2; PBX3; MYF6; ZSCAN18; ZNF215; FOXG1; KLF13; SOX3; FOXM1; FOXJ2; ZBED4; PAX5; TFAP2C; DDIT3; PFDN5; MED21; SHOX; FOXF1; ZNF180; RSF1; GATA6; DACH1; ZBED2; NFYB; SUZ12; SOX2; DBP; PITX2; NFATC3; HMGA2; ZKSCAN7; TOB1; NFE2L3; ZBTB18; SERTAD2; ZNF589; TULP3; ILF2; MNDA; ZNF112; ISL1; CBFA2T3; STAT4; VPS72; CREB1; E2F5; TOX; PSMC3; CUX2; YEATS4; IRF9; NKX2-1; PHIP; AR; BCL11A; HOXD1; ID3; ZNF217; CTBP1; TBL1X; HIC2; PAXBP1; LEF1; WNT4; SALL1; ZNF304; ESR1; ERBB4; AEBP1; ZEB1; ZNF331; POU2AF1; TBX3; MYB; ZNF423; ARID1A; STAT3; ZNF83; SUB1; SMAD3