Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69227	Diltiazem	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	333	HOXC10; HOXC6; TXNIP; PRKDC; PURA; ZHX3; ING2; EYA2; SKI; TCFL5; FOXD1; HOXC4; HMGB1; ZNF443; RFX2; DLX5; COPS5; MAGED1; MLXIP; NFIX; YWHAB; WHSC1L1; ERCC2; KLF12; DPF2; GTF2F1; MED20; RNF14; HSBP1; RCOR1; PIAS3; RELA; AEBP1; SOX12; HEY2; ZNF408; TP53; TRIP4; ZNF266; YEATS2; HDAC6; CUX1; ASH2L; MYB; VEZF1; TADA2A; SOX4; E2F2; KAT7; PRMT2; HABP4; PPARD; ARID3A; ADNP; MYC; NCOA1; HMG20A; HOXA1; ZKSCAN1; NR3C1; RBL2; MITF; CIITA; TRPS1; RNF141; RUNX3; MAZ; ZFP64; EZH1; IKZF1; ETV5; RUVBL2; NR2F2; ADRB2; LPIN2; PGR; ARID4A; BAZ1A; NR1D2; CBX6; BMI1; NUP62; TBP; MED7; BCLAF1; PRRX1; TRAF6; KMT2D; PLAG1; BHLHE40; ZKSCAN7; KLF9; LZTS1; SOX5; HOXC8; PAX8; LMCD1; KLF2; LEF1; NR1H3; KAT5; ZBTB40; HIVEP2; BLZF1; TFEC; ZBTB24; ZNF764; DDX5; ZNF783; TSG101; ZNF768; BATF; E2F5; RFX7; TFCP2; STAT2; ZBTB39; DNAJC1; PAX9; PSMD9; VGLL4; ZMYND11; NAB2; NRBF2; DYRK1B; ELF4; SREBF2; SMAD5; SSX1; BRF2; RELB; ID4; SUV39H1; BRPF1; IRF2; FOXO3; NFKBIB; PLAGL2; SOX10; RBBP7; ZNF337; DMRT1; UBE2I; HOXA11; RHOA; ZNF629; CTNNB1; ZNF143; HMGB3; RBL1; DRAP1; BRD8; NFIC; HTATIP2; POU2F2; NFATC3; GABPB1; EGR4; ZNF248; CLOCK; JUND; SIRT7; TWIST1; UBE2B; MECP2; SSRP1; FOXC1; ZNF217; TRIM32; GLI3; TGIF2; EN2; ATF1; MNT; PDLIM1; TAF12; HMG20B; TADA3; PREB; NCOA6; BCOR; SPIB; WHSC1; HOXA10; SMAD1; NSD1; MKL1; ZNF574; PBX2; ZNF696; CHD3; ELF3; PPARG; HCFC1; POU4F1; HMGA2; NPAS2; RXRA; FHL2; ATF6; TBPL1; PIR; MSX1; ZNF587; CBFA2T3; SNW1; EGR3; RSF1; SIAH2; RBBP5; XBP1; TFE3; E2F3; RB1; KDM2A; TBL1X; AATF; TSC22D4; HLTF; CRK; STAT5B; PRPF6; ELK3; MBD2; ZNF711; SIM1; FOXO1; SMARCA1; CEBPA; ZNF205; MEF2A; PHF8; EED; SFMBT1; CBX7; FOXO4; USP22; CENPF; TSC22D2; TERF2; SMARCA5; PARP1; NFIL3; PKNOX1; BARX2; NR2F6; ARNT; TFAP4; SIM2; KLF3; BRD2; UBTF; ACTL6A; BAZ1B; BRD3; TAF7; ZNF14; TSC22D3; ZBTB7A; NFKBIA; NFYB; TCEB2; HDAC4; SETD3; NEDD8; MEOX1; SMARCA2; NFAT5; IRF4; ZNF133; MED1; ZNF267; MYT1L; STAT4; RUNX1; SERTAD2; MAML1; ZBTB38; JUN; GTF3A; ZMYND8; PCBD1; CHD4; JAK2; CTBP2; NCOR2; NCOA2; EZH2; NPAT; TAF4; CCNA2; LHX6; GRHL2; ZNF419; TCERG1; EMX2; MYBL2; ZNF22; ENO1; BRD4; IKBKAP; ORC2; YBX1; ZNF7; DNAJC2; FOSL1; TCF7L1; BATF3; CTR9; KAT2B; WNT4; SLC2A4RG; TGFB1; SAP30; ZBTB1; TOB1; TLE1; CEBPB; KLF10; DEK; VPS72; MKL2; PHIP; STAT3; PHF20; ELF5; WT1; HIPK3; PCGF2; KDM5B; THAP11; WWTR1; TRIB3
Down-regulation	315	MTF2; LIN28A; HIRA; TCEA2; TFAP2A; RYBP; HDAC2; TAF5; ETS1; MNDA; HHEX; RNF138; CCNC; AES; CAMTA1; TBX3; FOXF2; RXRG; ZIC3; ZNF467; PBX1; SETD2; NRIP1; ATN1; HOXD1; PPRC1; TEAD4; THAP10; SOX9; CCDC59; ZNF10; SOX11; ZNF571; APEX1; IRF6; ST18; AIP; HAND1; ELF1; HOXB6; GATA6; XRCC6; SMARCD3; ARID5B; MEIS1; NANOG; HEY1; ZNF184; NHLH2; THAP4; PFDN5; BACH1; ZNF654; UTF1; ATF2; ZFPM2; CNOT2; SUPT5H; CNBP; HMGA1; ZNF165; IKZF3; PRDM14; ZBTB17; CSDC2; UBE3A; ZNF423; CREB3; NCOA4; IKZF5; HOXB5; BRD7; RBM39; BASP1; NEUROG2; HOXD3; DDIT3; LOXL2; ID3; ZSCAN31; SUB1; PMS1; PAXBP1; SOX18; ARNTL; TCF7; PIAS1; KDM5C; NKRF; CXXC1; LITAF; ZNF85; ZNF140; HBP1; RBFOX2; FOXF1; HOXD10; NEUROG1; CTCF; PAX5; ATOH1; IRX4; ZXDB; INSM1; HOXB13; NFYA; CUX2; MED17; ZNF273; TRIM29; MYF5; SOX14; FEZF2; NR2C1; ZNF432; HLX; CNOT3; ZNF532; PBX3; C1QBP; E2F4; CERS6; NR0B1; ABL1; ZNF12; ZNF75D; ZNF74; CDX1; TAF5L; STAT1; ZNF614; BCL11A; TFEB; ZNF32; GFI1B; HOXA4; CBFA2T2; YBX3; ZSCAN12; ZNF669; TCF21; MED27; TDP2; MED14; ADNP2; HSF1; MXI1; HSF4; BTAF1; PROX1; ANKRD1; PMF1; SUPT3H; ISL1; DLX2; TULP3; PRDM4; TULP2; FOXM1; ZNF195; MYF6; NR5A2; ZNF219; POU4F3; SIX1; NRL; PQBP1; NFE2L3; MAF; MED15; IRF9; ZBED2; TAF1D; MED21; CD3D; JUP; KLF7; FOXJ2; FOXH1; USP16; SCAI; ZNF675; SATB2; CSDE1; CBX3; ERF; ZNF239; PEG3; HDAC9; ZNF536; NKX3-1; ZNF580; USP21; SMAD4; NR4A3; EMX1; ZNF141; RLF; BRCA2; BCL6; ZNF350; NFIB; TRIM28; YEATS4; CRY1; ZNF232; THAP7; TRIP6; ZEB1; PITX2; COPS2; DAXX; FOXJ3; DCC; TBX2; ABT1; ZNF131; EHF; POU2AF1; HMGB2; MYRF; NKX2-2; ZNF384; TGFB1I1; CHD9; MED13; CNOT1; ZNF263; ZNF394; ZNF84; CREG1; HESX1; POU5F1B; REL; NR1H2; ZNF215; ZZZ3; TGIF1; SALL1; SFPQ; KLF11; NFX1; ZNF302; ERBB2; DR1; ZNF529; IFI16; ZNF44; NKX2-1; HMGXB4; SMAD3; HOXD11; IRF3; PBXIP1; STAT6; TAF10; SIRT2; ZNF43; SCAND1; CRYM; ZMIZ1; INSR; ASXL1; ZNF589; HOXA7; RBPMS; ZFP36L1; CEBPD; ZNF91; CITED2; ATF4; CERS4; MEF2C; FOXN3; CREB3L2; FOS; PHOX2B; PSMC3; JUNB; ZNF148; BTF3; ARID4B; RBBP8; NR2F1; AHR; BIRC2; HOXB2; DACH1; ZNF331; ZNF426; BHLHE41; SNAI2; HOXA5; KAT6B; BAZ2B; SPEN; MECOM; MYCL; TOX; SMAD6; MYCN; PSIP1; TCF7L2; SOX17; TFDP2; ATF3; KLF4; RFX5; TAL1; EPAS1; GATA2; DMTF1; TSC22D1; SSBP2; KDM5D