Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID69224	Leflunomide	GSE92742	PHH	Human	24h	10uM	EID0376

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	E2F2; KDM5D; HMGA2; FOXI1; SOX4; ZBTB24; BRWD1; CDK9; PRDM2; ERBB4; MNDA; OVOL2; LIMD1; FUBP1; HOXC4; SP3; KMT2A; HEY2; ZNF467; ZNF107; DLX5; TRIM27; DMRT1; ZFHX3; RBBP8; PAWR; SOX5; MYCL; E2F8; SAP30; NCOA6; LMCD1; RNF138; TFEC; SP140; ZNF266; CBX5; TERF1; DMTF1; TFCP2L1; MEN1; SFPQ; TGFB1; ZNF239; SMAD2; SCAND1; ID3; HOXB7; SOX9; DDX54; MAGED1; MBD2; ZNF117; ZKSCAN1; ATF7IP; FOXN3; OLIG2; BAZ2A; MAX; GFI1; NR1H4; SHOX; TRIM22; SOX17; ZNF175; SMARCC2; ADNP; ZBTB20; ZNF711; HIC2; LPIN2; ZFP36L2; ZMYM2; HOXB6; FHL2; CREB3L2; AFF1; FOXE1; ELF4; USP16; TFAP2C; NR0B1; PHF20; NR4A2; IKBKAP; JUP; MYB; GATA2; E2F3; FLNA; LEF1; ETS2; TAF1D; BTG1; CTBP2; TCF7L2; NFATC3; CEBPB; TFDP2; SMARCA1; NKX2-2; SALL1; WT1; HMGN3; MYBL1; POLR2A; SATB1; TRPS1; CREB3L1; ESR1; ASCL1; CEBPA; DLX2; IRF9; INSR; ZSCAN18; KLF2; KAT6B; THAP11; TRIB3
Down-regulation	129	ZFX; KDM5C; NRIP1; CDK8; HMBOX1; CCNT1; MED14; SUPT4H1; CHD3; NUP62; ZNF576; NFKB1; TBPL1; ALX1; ZNF669; NONO; MAFG; SNAI2; ZNF143; POLR3C; CITED1; EHF; ATF2; TOPORS; CDX2; KLF7; RELB; TCEA1; FOXN2; ZNF222; SKIL; COPS5; NFE2L1; ZNF131; CNOT1; MDM4; BHLHE41; ZNF45; MLX; ZNF274; PNRC1; STAT6; CREBL2; PTTG1; CUX2; PHF8; EGR2; FOSL1; TFAM; PRDM1; KLF5; MAF; PURA; MTDH; ZBTB38; RHOA; MAFF; NR4A3; MXI1; SP100; MED4; GLI2; NR3C2; STAT5A; MITF; EED; SKI; CD3D; RBL2; EP300; MEOX1; NFIL3; KLF9; RYBP; DRAP1; TOB1; JUND; REL; BRD4; PEG3; ISL1; XBP1; NCOR2; ATF1; LOXL2; ZNF148; PITX2; DACH1; NR1H2; CBFB; HOXD1; RB1; FOXF2; TRIM16; EGR3; PIR; HIVEP2; CHD7; ATF6; YBX3; RBFOX2; ZNF529; STAT1; ZMIZ1; ZBTB18; LITAF; CERS4; DNMT3B; ZFPM2; RBPJ; YBX1; RBPMS; SAP18; SPEN; SMAD5; ELF5; BMI1; NR2F1; FOXM1; ATF3; MSX1; HOXA5; TOX; ZNF217; EMX2; HES1; FOXF1; RFX5; KDM5A